Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res. 2009; 19 :128–39. doi: 10.1038/cr.2008.328. [ Cross Ref ]Zhang YE ( 2009 ). Non-Smad pathways in TGF-beta signaling . Cell Res 19 : 128 – 139 .Ying E Zhang. Non-Smad pathways in TGF-β signaling[J]. 2009.doi:...
Transforming growth factor-β utilizes a multitude of intracellular signaling pathways in addition to Smads to regulate a wide array of cellular functions. These non-canonical, non-Smad pathways are activated directly by ligand-occupied receptors to reinforce, attenuate, or otherwise modulate downstream ...
Non-Smad pathways in TGF-|[beta]| signaling 来自 NCBI 喜欢 0 阅读量: 322 作者: YE Zhang 摘要: 转变生长因素 -- 尾除了 Smads 利用大量的细胞内部的发信号小径调整细胞的功能的一个宽数组.这些不在经典中, non-Smad 小径被占据 ligand 的受体直接激活到增强,稀释,或不那样调制下游地细胞的回答.这些 ...
TGF-beta: an emerging player in drug resistance. Cell Cycle 2013; 12: 2960–2968. 11. Lamouille S, Xu J, Derynck R. Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 2014; 15: 178–196. 12. Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res ...
ZHANG C,ZHANG X,XU R,et al.TGF-beta2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells' invasion[J/OL].J Exp Clin Cancer... C Zhang,X Zhang,R Xu,... 被引量: 0发表: 2018年 Signaling pathway cooperation in TGF-β-induced epithelial–mesenchymal transition Trans...
in the regulation of specific cellular signaling pathways, such as TGF-β and WNT, that act to regulate cytokine secretion and extracellular matrix synthesis [11,12,13]. A growing body of evidence points to cross-regulation between these two pro-fibrotic pathways mediated via ncRNAs, and its ...
Non-Smad TGF-b signalsNon-Smad TGF-b signalsMoustakas, AHeldin, C.HMoustakas A & Heldin CH 2005 Non-Smad TGF-b signals. Journal of Cell Science 118 3573-3584. (doi:10.1242/jcs.02554)Moustakas, A. and Heldin, C.H. (2005) Non-Smad TGF-b signals. J. Cell Sci. 118, 3573-3584...
The formin protein formin-like 1 (FMNL1) plays a key role in... XYY A,JJL B,WRX C - 《Biomedicine & Pharmacotherapy》 被引量: 0发表: 0年 Ski prevents TGF-beta-induced EMT and cell invasion by repressing SMAD-dependent signaling in non-small cell lung cancer Epithelial-mesenchymal ...
Jun Hwan Kim1, Jae Young Lee1, Yoe-Sik Bae1, Seung-Hoi Koo3, Seong-Jin Kim5 & Seok Hee Park1 Transforming growth factor (TGF)-b, a pivotal cytokine involved in a variety of cellular functions, transmits signals through Smad-dependent canonical and Smad-independent noncanonical pathways. ...
We investigated the effects of TGF-beta(1) on the cellular functions of intestinal epithelial cells, and also evaluated its signaling pathways in these cells.We used the rat IEC-6 intestinal epithelial cell line for these studies. The expression of TGF-beta(1)/Smad signaling molecules was ...