Firstly, the MTBC-IS6110-nested PCR was validated in non-invasively collected specimens, in terms of its specificity and sensitivity, and then compared with those of the invasively collected oral and rectal swabs in 24 captive MTBC-suspected Mf. After validation, these methods we...
Isolates with smooth to greasy, domed, nonchromogenic colonies were recovered from all submitted samples using both 7H11 agar and MGIT broth (Becton Dickinson, Fukushima, Japan) and identified as MTBC using loop-mediated isothermal amplification (Eiken Chemical, Tokyo, Japan) and TaqMan PCR (Roche...
(Becton Dickinson, Sparks, USA) if i) the sample originated from a sterile site, ii) the sample originated from a non-sterile site, and a previous positive mycobacterial culture was MTBC-negative, iii) the patient has cystic fibrosis, iv) there is clinical data to support NTM infection and...
Objectives Sequence analysis of known antibiotic resistance genes of the Mycobacterium tuberculosis complex (MTBC) is increasingly being used to infer phen... Feuerriegel,Silke,Köser,... - 《Journal of Antimicrobial Chemotherapy》 被引量: 71发表: 2014年 The Tuberculosis Drug Discovery and Developmen...
Interestingly, a majority of these TA pairs are present in pathogenic bacteria such as the MTBC (marked in green) and shared a sequence identity of greater than 80% amongst themselves (Fig. 8). Others such as Mycobacterium avium, Mycobacterium chimaera, Mycobacterium gordonae, Mycobacterium ...
Wildlife, on the other hand, is thought to be a reservoir for certain members of the Mycobacterium tuberculosis complex (MTBC), such as M. caprae, which causes tuberculosis in cattle and red deer. Methods Switzerland implemented a surveillance program for tuberculosis in wild animals in 2014. ...
The insertion sequence IS6110 is frequently used as a marker for the presence of ancient DNA (aDNA) derived from bacteria of the Mycobacterium tuberculosis complex (MTBC) in human archaeological remains. The specificity of polymerase chain reactions (PCRs) directed at IS6110 has, however, been ...
In conclusion, our breakthrough method enables rapid and accurate detection of both MTBC and NTM bacteria within the BACTEC MGIT system. This approach represents a valuable tool in clinical settings for distinguishing between MTBC and NTM infections, thereby enhancing the management and control of ...
While the clinical presentation of Mycobacterium tuberculosis complex (MTBC) and NTM may resemble each other, their treatment regimens differ significantly. The aim of this study is to comprehensively investigate and characterize the clinical and microbiological aspects of NTM in presenting presumption TB ...
Bronchiectasis in the imaging (74.6% VS 47.0%, I P i = 0.008), positive acid-fast staining of sputum smear (38.8% vs 11.8%, I P i = 0.005), the proportion of anti-mycobacterium tuberculosis complex (MTBC) treatment history (31.3% VS 8.8%, I P i = 0.013) and anti-NTM treatment ...