We further restricted our cohort to non-diabetic, obese men by excluding men with a prior diabetes mellitus diagnosis, a hemoglobin A1c > 6.5%, or having ever received insulin or metformin. Men were then stratified into cohorts of those that did and did not receive a semaglutide ...
van Popele N M, Westendorp I C, Bots M L, Reneman R S, Hoeks A P, Hofman A, Grobbee D E, Witteman J C. Variables of the insulin resistance syndrome are associated with reduced arterial distensibility in healthy non-diabetic middle-aged women. Diabetologia, 2000, 43(5): 665-672...
although these too overlook the hepatic implications and NAFLD. In addition to the direct adverse effects these therapies have on the liver, the treatments likely lead to an enhanced risk of NAFLD through an increase in body weight and/or reduction in lean mass, with lipid and glucose-insulin ...
Keywords: non-alcoholic fatty liver disease;NAFLD;NASH;metabolic syndrome;insulin resistance;obesity;depression;anxiety;stress;health related quality of life
(p< 0.05). In non-obese participants, glucose levels were significantly higher after 36 h compared to 12 h fasting at 120 min of OGTT (109 ± 31 mg/dL vs. 79 ± 18 mg/dL;p= 0.001) but insulin levels were lower after 36 h of fasting at 30 min of OGTT (41.2 ± 34.1 mU/L ...
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