Center for the Prevention and Management of Overweight and Obesity, Division of Clinical and Translational Research in Endocrinology, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, ‘Aghia Sophia’ Children’s Hospital, 11527 Athens, Greece ...
Figure 1. PRISMA flow chart of the study selection process. 3.2. Characteristics of Included Studies The main characteristics of the included RCTs are summarized in Table 1. A total of 8249 adults treated with liraglutide were evaluated. The mean age was 45.9 ± 5.5 years and 24% of patien...
homeostatic model assessment for insulin resistance; WHR, waist-to-hip ratio; ALP, alkaline phosphatase; DHEAS, testosterone, and dehydroepiandrosterone sulfate levels; HDL, high-density lipoprotein; UA, uric acid; ALT, alanine aminotransferase; MAP, mean arterial pressure; FPG, fasting plasma glucose...
It is noteworthy that the authors observed a positive association between epicardial fat thickness and markers of inflammation and insulin resistance, both being common findings in NAFLD [9]. The interpretation of a standardized mean difference as an effect size may be challenging in clinical ...
One year after surgery, the two groups of patients had significantly reduced weight, BMI, insulin, HOMA-IR, triglycerides, and uric acid, and increased HDL cholesterol (Table 1, t = 1,p0–1, pairedttest). A comparison between responder (R) and non-responder (NR) patients showed that, on...
Regionally, increased incidences of type-2 diabetes, obesity, cancer, CVD, and other diet-related NCDs among adults are becoming the main public health concern in most Arab countries [5,6]. The intake of energy-dense foods is negatively influencing public health care and social and economic pr...
as for the pharmaceutical treatment of the participants, 18%, 28%, 13%, 40%, 13%, 10%, 3%, and 48% of them received angiotensin receptor blockers (ARBs), angiotensin converting enzyme inhibitors (ACE inhibitors), diuretics, beta blockers, calcium antagonists, oral antidiabetics, insulin,...
Currently, non-alcoholic fatty liver disease is the most common liver disease worldwide, with a prevalence of 32%. It is much more common among men (40%) and among patients with metabolic comorbidities such as obesity, diabetes and dyslipidemia. Being an
and immunohistochemical studies were performed to elucidate the mechanism of swietenine’s effect in NAFLD. The critical regulators (genes and proteins) involved in lipogenesis (ACLY, ACC1, FASN, SREBP1c, and ChREBPβ) and oxidative stress (Nrf2, NQO-1 and HO-1) pathways were determined. In...
Ahmed EA, El-Derany MO, Anwar AM, Saied EM, Magdeldin S. Metabolomics and Lipidomics Screening Reveal Reprogrammed Signaling Pathways toward Cancer Development in Non-Alcoholic Steatohepatitis.International Journal of Molecular Sciences. 2023; 24(1):210. https://doi.org/10.3390/ijms24010210 ...