Immune-mediated heparin-induced thrombocytopenia constitutes a potentially life-threatening complication of heparin therapy requiring immediate switch to nonheparin ... KG Fischer - 《Hemodialysis International》 被引量: 175发表: 2010年 Nonheparin Anticoagulants for Heparin-lnduced Thrombocytopenia. A letter...
Nonheparin anticoagulants for heparin-induced thrombocytopenia. N Engl J Med. 2013;368(8):737- 44. http://dx.doi.org/10.1056/NEJMct1206642. PMid:23425166.Bhatt VR, Aryal MR, Armitage JO. Nonheparin anticoagu- lants for heparin-induced thrombocytopenia. N Engl J Med 2013;368:2333--4....
Once formed, a blood clot in a leg can increase in size or can move to the lungs and the recommended treatment is to give drugs that thin the blood (anticoagulants). These include heparins and drugs that inhibit the action of vitamin K (warfarin, phenprocoumon, and acenocoumarol). The ...
Non-vitamin K antagonist oral anticoagulants (NOACs) are replacing warfarin and heparins in several clinical situations. With varying modes of action, the effects of NOACs on thrombus formation, integrity, and lysis is unknown. To determine whether two techniques of thrombelastography (TEG) and a...
Anticoagulants (36.9 % vs. 26.1 %) and aspirin (56.9 % vs. 45.0 %) continued to be prescribed more frequently to diabetics, but without statistical significance anymore. Of note, antiarrhythmics were prescribed significantly more often in diabetic patients at discharge (15.4 % vs. 5.2 %). ...
(n=1306) Patient refusal Physician's choice Already taking other anticoagulants drugs for other medical conditions Taking medication is contraindicated 258 (9.5) 2094 (77.4) 110 (4.1) 242 (8.9) 87 (6.2) 1181 (84.5) 52 (3.7) 78 (5.6) 171 (13.1) 913 (69.9) 58 (4.4) 164 (12.6) ...
nervous system metastases, use of antiaggregant treatments (aspirin ≥325 mg per day, clopidogrel, ticlopidine, or dipyridamole), anti-vitamin K drugs at a curative dose, treatment with low-molecular-weight heparin at a curative dose, and treatment with non-steroidal anti-inflammatory drugs. The...
Warfarinised patients frequently present for total knee arthroplasty (TKA). Current practice of heparin ‘bridging’ is potentially cumbersome and hazardous. The research question is if cessation of warfarin is necessary for TKA. The study design was a r
; 4) platelet count <100,000/mm3; 5) neutrophil count <1800/mm3; 6) increased risk of bleeding; and 7) recent (within 10 days) or planned use of nonpermitted concomitant medications (any antiplatelet agent other than ASA, oral anticoagulants, hirudin, nonsteroidal anti-inflammatory drugs)....
If two different new drugs are approved with the -margin approach by using the same active control, it implies that four noninferiority trials share the same active control. Sharing the same active control generates dependencies among trials. In this paper we investigate how much such dependencies...