Cholesterol conjugates are common: they are a specific type of lipid conjugates, where a cholesterol group is added to one of the ends of the oligonucleotide, facilitating the interactions between the oligonucleotide and the circulatory lipoprotein particles and promoting delivery [123,133]. The ...
Finally, the lipid profile measurements, including triglycerides, total cholesterol level, and LDL-C (low-density lipoproteins), were markedly higher in the obese compared to lean subjects, while the HDL-C (high-density lipoprotein) was significantly lower in the former group (Table 1). Subjects...