EVIDENCE‐BASED ANSWER Compared with fasting lipid levels, nonfasting total cholesterol, low‐density lipoprotein (LDL), and highdensity lipoprotein (HDL) levels in both children and adults differ minimally. Although triglyceride levels can vary the most—by as much ...
However, if postprandial effects do not substantially alter lipid levels or their association with cardiovascular risk, then a nonfasting blood draw has many practical advantages.1 Indeed, recent studies suggest that postprandial effects do not weaken, and even may strengthen, ...
lipid levels (for HDL, non-HDL, and LDL), irrespective of fasting status.58 Finally, from a practical standpoint, performing nonfasting lipid assessments in routine clinical care might obviate many of the serious challenges associated with prolonged fasting, namely the possibility of decreased ...
Fasting for >8 h, as previously required for lipid profiles, normally only occurs a few hours before breakfast. By contrast, the nonfasting state predominates most of a 24-h cycle and better captures atherogenic lipoprotein levels. Plasma contains atherogenic lipoproteins of hepatic origin in the ...
Body mass index (BMI) and lipid parameters are the most commonly used anthropometric parameters and biomarkers for assessing nonalcoholic fatty liver disease (NAFLD) risk. This study aimed to assess and quantify the mediating role of traditional and non-
In this Review, we provide an overview of the contribution of metabolomics and lipidomics in clinical studies to identify biomarkers associated with NAFLD and nonalcoholic steatohepatitis (NASH). In addition, we highlight the key metabolic pathways in NAFLD and NASH that have been identified by ...
(Yoon et al.2021). Because of impaired lipid metabolism, NAFLD patients experience inter- and intrahepatic lipid buildups such as enhanced hepatic FFA intake and very-low-density lipoprotein synthesis, dysregulation of triglyceride export, and reduced levels of high-density lipoproteins and cholesterol...
In the present study, we found that the AUC of TG/HDL-C for detecting NAFLD is 0.79 in men and 0.85 in women, significantly higher than that of other lipid parameters and markers of liver injury. Thus, TG/HDL-C may be a potential surrogate for NAFLD. Though the mechanism underlying ...
et al. The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity. J. Biol. Chem. 281, 934–944 (2006). Article CAS PubMed Google Scholar Xu, A. et al. Angiopoietin-like protein 4 decreases blood ...
Docosahexanoic Acid (DHA) Improved Glucose and Lipid Metabolism in KK-A^y Mice with Genetic Non-Insulin-Dependent Diabetes Mellitus The hypoglycemic and hypolipidemic effect of docosahexaenoic acid (DHA; C22 : 6蠅-3) ethyl ester was examined in KK-A^y mice and neonatal streptozotocin-in... S...