Define nonspecifically. nonspecifically synonyms, nonspecifically pronunciation, nonspecifically translation, English dictionary definition of nonspecifically. adv in a nonspecific way Collins English Dictionary – Complete and Unabridged, 12th Edition 2
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observed levels of homozygosity vary substantially between families (Fig.1a). To illustrate the impact of overall homozygosity we often subdivide the HMCA sample into high and low homozygosity families throughout the manuscript. Families were classified as highly homozygous if at least one child was ...
and humans are the product of complex interactions amongst the sex hormones, genetic variability, and the environment. However, all these factors function on the background created by the sex determination pathway, XX or XY. The sex determination decision of XX or XY must result in sexual dimorp...
Hardy–Weinberg expectations (Population data) or Mendelian segregation expectations (Family data, except for loci homozygous for different alleles between the two parents, which are thus not sex-linked). Note that there is the possibility of removing sex-linked markers using such a filter if the ...
96 For example, the loss-of-function mutation in the H3K27me3 demethylase gene KDM6A/UTX mainly occurs in male-biased cancers.96,102,103 However, female cancers with KDM6A mutations usually require homozygous mutations, leading to lower female incidences.102 Other than disease incidence, gender...
The numbers in the names of HSPs refer to the approximate molecular weight of the proteins in kilodaltons (kDa). For example, HSP40 proteins have a molecular weight around 40 kDa, and HSP60 proteins are around 60 kDa. These designations help to differentiate the proteins based on their ...
The raolluscan fauna of a special habitat, the high intertidal algal turf, was studied at four stations on the island of Sao Miguel, Azores. The number of ... JMN Azevedo - 《Biological Journal of the Linnean Society》 被引量: 8发表: 2010年 A novel PLEC1 nonsense homozygous mutation (...
For example, if one of the two copies of a chromosome or portion of a chromosome is deleted, then the expression will be monoallelic for genes within the impacted genomic region because all expression emanates from the one remaining allele. It is important to note that aneuploidy can be ...
(R26)locus, which ensures robust transcription under theR26promoter. KI mice were then crossed withCMV-Cremice so that homozygousCIP2A-BP+/+mice were obtained, which show constitutive and ubiquitous CIP2A-BP translation. Finally,CIP2A-BP+/+mice were further crossed with breast cancer-proneMMTV-...