Simple fatty liver disease (steatosis) is a benign condition, reversible by weight loss. Inflammatory cell infiltration leading to non-alcoholic steatohepatitis (NASH) is a more aggressive condition, which is present in up to 10 % of cases and may lead to varying degree of fibrosis and ...
NAFLD comprises a histological spectrum of liver damage ranging from simple steatosis to non-alcoholic steatohepatitis (NASH) which may progress to fibrosis, cirrhosis, and HCC. From: Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease, 2013 ...
Non-alcoholic fatty liver disease (NAFLD) has emerged pandemically across the globe and particularly affects patients with obesity and type 2 diabetes. NAFLD is a complex systemic disease that is characterised by hepatic lipid accumulation, lipotoxicity, insulin resistance, gut dysbiosis and inflammation...
Non-alcoholic fatty liver disease (NAFLD) has been shown to influence breast cancer progression, but the underlying mechanisms remain unclear. In this study, we investigated the impact of NAFLD on breast cancer tumor growth and cell viability through the potential mediator, hepatic fibroblast growth ...
NAFLD是指除外酒精和其他明确的损肝因素所致的肝细胞内脂肪过度沉积为主要特征的临床病理综合征,与胰岛素抵抗和遗传易感性密切相关的获得性代谢应激性肝损伤。包括单纯性脂肪肝(SFL)、非酒精性脂肪性肝炎(NASH)及其相关肝硬化。非酒精性脂肪性肝病除可直接导致失代偿期肝硬化、肝细胞癌和移植肝复发外,还可影响其他慢性...
Non-alcoholic fatty liver disease (NAFLD), which approximately affects a quarter of the world’s population, has become a major public health concern. Although usually associated with excess body weight, it may also affect normal-weight individuals, a condition termed as lean/non-obese NAFLD. The...
Nonalcoholic Fatty Liver Disease Nonalcoholic fatty liver disease (NAFLD) represents a spectrum from isolated hepatic triglyceride accumulation (steatosis) through hepatic triglyceride accumulation plus inflammation (nonalcoholic steatohepatitis, NASH) and ultimately progressing to fibrosis/cirrhosis and ...
Liver fibrosis in patients with non- alcoholic fatty liver disease: diagnostic options in clinical practice. Expert Opin Med Diagn 2012;6:381-394.Boursier,J.,Rousselet,etc.Liver fibrosis in patients with non-alcoholic fatty liver disease: Diagnostic options in clinical practice[J].2012,5(5)....
The nonalcoholic fatty liver disease (NAFLD) is defined as the presence of hepatic steatosis, determined by either imaging or histology, in the absence of secondary causes of hepatic fat accumulation. Nonalcoholic fatty liver is defined as the presence of hepatic steatosis with no evidence of ...
Nonalcoholic fatty liver disease (NAFLD) is a dynamic chronic liver disease that develops in close association with metabolic irregularities. Between 2016 and 2019, the global prevalence among adults was reported as 38% and among children and adolescents it was about 10%. NAFLD can be progressive...