At a node of Ranvier the axon is reduced in diameter; on the largest mammalian fibres the reduction is to less than half of the internodal diameter. The axoplasm at the node has optical properties different from the internodal axoplasm, but there is no visible transverse boundary across it. ...
The meaning of NODE OF RANVIER is a small gap in the myelin sheath of a myelinated nerve fiber.
Ranvier's nodes medullary sheath,myelin sheath- a layer of myelin encasing (and insulating) the axons of medullated nerve fibers opening,gap- an open or empty space in or between things; "there was a small opening between the trees"; "the explosion made a gap in the wall" ...
Nodes of Ranvier are located on A) Schwann cells B) neuronal cell bodies C) oligodendrocytes D) neuronal axons. Myelinated Axons: Axons of neurons can be found either myelinated or non-myelinated. Myelination of an axon is similar to the in...
The node of Ranvier is rich in Na+channels, which are crucial for action potential conduction, adhesion molecules such as Nrcam and Nf186, and cytoskeletal adaptor proteins, such as ankyrin G and spectrin βIV. In addition, Schwann cell microvilli cover the nodal gap in the peripheral nervous...
The architecture and function of the nodes of Ranvier depend on several specialized cell contacts between the axon and myelinating glial cells. These sites contain highly organized multimolecular complexes of ion channels and cell adhesion molecules, closely connected with the cytoskeleton. Recent findings...
The architecture and function of the nodes of Ranvier depend on several specialized cell contacts between the axon and myelinating glial cells. These sites contain highly organized multimolecular complexes of ion channels and cell adhesion molecules, closely connected with the cytoskeleton. Recent findings...
Specific cell adhesion molecules (CAMs) are dedicated to the formation of axo-glial contacts at the nodes of Ranvier of myelinated axons. They play a central role in the organization and maintenance of the axonal domains: the node, paranode, and juxtaparanode. In particular, CAMs are essenti...
with antibodies specific for the ecto-domain, also was found to be coexpressed with neurofascin at nodes of Ranvier and at axon initial segments. This... The Rockefeller University Press - 《Journal of Cell Biology》 被引量: 622发表: 1997年 Molecular composition of the node of Ranvier: iden...
High densities of ion channels at axon initial segments (AISs) and nodes of Ranvier are required for initiation, propagation, and modulation of action potentials in axons. The organization of these membrane domains depends on a specialized cytoskeleton consisting of two submembranous cytoskeletal and ...