The workup excluded an infectious or autoimmune disease, but IgG κ monoclonal protein was detected in serum at a concentration of 0.4mg/dL. Because there was a mismatch between the serum monoclonal protein (IgG κ) and immunofluorescence staining pattern (nonspecific IgM, no light chain ...
A dot immunobinding assay for the detection of a circulating mannoprotein (MP) antigen of Candida species in the sera of neutropenic patients in a hematological setting is described. The technique is based on the use of a monoclonal antibody which recognizes an oligomannoside epitope shared by ...
Splenomegaly can be detected in some patients with systemic lupus erythematosus (Chapter 274), certain drug reactions, and serum sickness. Malignancies of the immune system and nonimmune organs can also lead to splenomegaly. Splenomegaly is usually seen in patients with chronic myeloid leukemia and ...
MYC protein expression is detected in plasma cell myeloma but not in monoclonal gammopathy of undetermined significance (MGUS). Am. J. Surg. Pathol. 38, 776–783. https://doi.org/10.1097/PAS.0000000000000213 (2014). Article PubMed Google Scholar Moller, H. E. H. et al. Myc protein ove...
The workup excluded an infectious or autoimmune disease, but IgG κ monoclonal protein was detected in serum at a concentration of 0.4 mg/dL. Because there was a mismatch between the serum monoclonal protein (IgG κ) and immunofluorescence staining pattern (nonspecific IgM, no light chain ...
2d, e). Similarly, treatment with PA reduced the Noc4l protein levels in a dose-dependent manner in RAW264.7 cells (Fig. 2f). We also detected reduced NOC4L protein expression in macrophages derived from THP1 (a human monocyte cell line) after LPS treatment (Fig. 2g). Deletion of No...
CD14 monoclonal antibody (APC) (17-0149-41, eBioscience, USA) or PE anti-mouse/human CD11b (101207, BioLegend, USA) fluorescent antibody was added to the cell suspension and incubated for 30 min away from light. The proportions of CD14- and CD11b-positive cells were detected via flow ...
Mannoprotein is defined as a glycoprotein present on the surface of pathogenic fungi, such as Candida, consisting mainly of mannose residues with various linkages like α1-2, α1-3, α1-6, and β1-2. It plays a role in host-pathogen interactions and can vary in structure based on the...
These receptors include carcinoembryonic adherence molecules, which are the major class of opacity protein recep- tors49 and the human CR3 molecule,50 which although having a high degree of similarity to that of mice, is likely to be host restricted in that a monoclonal antibody that blocks go...
Conversely, endogenous NOLC1 was detected in the immunopre- cipitate obtained using an anti-TRF2 antibody (Figure 1d). Our results demonstrated that NOLC1 interacted with TRF2, which is consistent with the previous result that NOLC1 is found in the TRF2-interacting protein pool in 293T ...