As the study of biological processes has progressed to the molecular level understanding of the underlying mechanisms has required determination of the three-dimensional structures of the molecules involved, their ability to undergo structural interconversions, and the interactions among them. For molecules...
nucleic acidschemical equilibria, complexation equilibriamagnetic resonance, nuclear quadrupole resonance (organic substancesC NMR spectra were recorded for chloroform solutions of 2',3'-O-isopropylidene-5'-O-acetyladenosine (1), 2',3',5'-O-tribenzoyluridine (2), 2',3'-O-isopropylidene-5'-O-...
NMR studies on protein-nucleic acid interaction A special section of this issue is devoted to the study of protein-nucleic acid interaction by NMR. This topic constitutes a fruitful area of research alre... R Kaptein - 《Journal of Biomolecular Nmr》 被引量: 0发表: 2013年 The pH-modulation...
Within the last several years, a number of exciting, pioneering ^(15)N NMR studies of biomolecules have been reported, and this review will describe several of these in three areas of biochemistry: (1) proteins including proteolytic enzymes and hemoproteins, (2) nucleic acids and nucleotide ...
The potential of organic acids to inactivate foodborne pathogens in food industry has gained attention, while the sanitizing mechanism of acid stress has not been explained fully at metabolomics level. The aim of this study was to elucidate the antimicrobial mechanism of low-concentration organic acids...
NMR spectroscopy is a powerful experimental technique to study biological systems at the atomic resolution. However, its intrinsic low sensitivity results in long acquisition times that in extreme cases lasts for days (or even weeks) oft... V Kocman,GMD Mauro,G Veglia,... - 《Solid State Nucl...
Their interaction with various nucleic acid conformations was examined in detail in terms of affinity constant ... S Bianco,C Bazzicalupi,P Gratteri,... - 《Cancer Research》 被引量: 0发表: 2011年 NMR spectroscopic study on interaction of the alkaloid palmatine with parallel d-(TTAGGGT)4 ...
- 《Nucleic Acids Research》 被引量: 38发表: 2003年 NMR Studies of DNA Single Strands and DNA:RNA Hybrids with and without 1-Propynylation at C5 of Oligopyrimidines ?,# The addition of the propynyl group at the 5 position of pyrimidine nucleotides is highly stabilising. We have determined...
A sequential assignment strategy for nucleic acids is proposed and illustrated by the assignments of the base and sugar protons of OL1.关键词: Biophysics DNA Structure Protein-DNA Interaction DOI: 10.1073/pnas.81.1.130 被引量: 152 年份: 1984 ...
- 《Nucleosides Nucleotides Nucleic Acids》 被引量: 46发表: 2002年 INTERACTION OF DISTAMYCIN A AND NETROPSIN WITH QUADRUPLEX AND DUPLEX STRUCTURES: A COMPARATIVE 1H-NMR STUDY Homonuclear NMR techniques have been used to investigate the interactions of the minor groove binding agents distamycin A (...