Occhipinti R , Somersalo E , Calvetti D . ( 2011 ) Interpretation of NMR spectroscopy human brain data with a multi-compartment computational model of cerebral metabolism . Adv Exp Med Biol 915 : 249 – 254 .Occhipinti, R., E. Somersalo, and D. Calvetti. Interpretation of NMR ...
We then inspected the 1D1H-NMR properties of the TMSiPhe decorated protein. NMR spectroscopy of β-arr1 H295TMSiPhe revealed a unique1H-NMR peak at 0.25 ppm, which is well separated from the other endogenous1H-NMR signals from β-arr1, providing a distinct NMR probe for the examinatio...
We present a method that measures the accuracy of NMR protein structures. It compares random coil index [RCI] against local rigidity predicted by mathematical rigidity theory, calculated from NMR structures [FIRST], using a correlation score (which asses
NMR spectroscopy is ideally suited for elucidating reaction mechanisms because it can simultaneously provide information on protein structure and reaction kinetics. Structural information is available primarily in the form of chemical shifts [20,21], but also through residual dipolar couplings [22], chemi...
3 In NMR spectroscopy, an external magnetic field is applied to a molecule and the nuclei of some isotopes (e.g.1H, 13C) absorb radio waves of specific frequencies to change their nuclear spin. In 13C NMR for example, any small changes in the local environment of the atom in the ...
High-resolution zero-field NMR J-spectroscopy of aromatic compounds. We report the acquisition and interpretation of nuclear magnetic resonance (NMR) J-spectra at zero magnetic field for a series of benzene derivatives, demo... John W. Blanched,MP Ledbetter,T Theis,... - 《Journal of the Am...
The particle size distribution of FW averaged at 1250 nm, obtained by DLS (Fig.2). In addition, the rock heterogeneity was qualitatively observed from the frequency graph of the pore throat diameter (Fig.3). The fraction of pores (y-axis) was calculated as the volume of injected mercury ...
, C-MoR MS, NMR Tutor, and C-MoR NMR) that we use extensively in our chemistry majors Spectroscopy and Instrumentation course to teach the theory, instrument design and function, and spectral interpretation skills that are essential to appreciating the full power of modern NMR Spectroscopy....
NMR spectroscopy has been extensively used to detect a wide range of low molecular weight endogenous metabolites in body fluids and tissue extracts. It is rapid, non-destructive, rich in quantitative information and allows simultaneous investigation of the predefined set metabolites30,31. Currently, ...
NMR spectroscopy, typically placed below 30 kDa, was overcome by Transverse Relaxation-Optimized SpectroscopY (TROSY)2. The TROSY enhancement, initially established for amide groups, was subsequently also realized for selectively methyl-labeled proteins (methyl-TROSY)3,4. Methyl-TROSY has since ...