Manual or automated NMR data processing for routine workflows—Fourier transformation, calibration, peak picking, integration, multiplet analysis, solvent detection, reference selection, etc. Exclude impurity signals and artifacts Automatic alignment and attachment of 1D curves upon import for spectra Attach...
Manual or automated NMR data processing for routine workflows—Fourier transformation, calibration, peak picking, integration, multiplet analysis, solvent detection, reference selection, etc. Exclude impurity signals and artifacts Automatic alignment and attachment of 1D curves upon import for spectra ...
The spectrum that was used in the task was clear and did not have any impurity or solvent peaks (Figure 4). Integration values and multiplicities were not provided. The students can determine the individual peaks based without 454 S. Gamage et al.: An exploration of the proton NMR problem-...
impurity profilingmetabolite analysisHigh performance liquid chromatography-solid phase extraction-nuclear magnetic resonance (HPLC-SPE-NMR) is a novel hyphenation technology that concentrates single chromatographic peaks to elution volumes matching those of NMR flow probes. The SPE unit facilitates the ...
impurity underlies the peaks of interest. This is done using chromatographic methods in combination with 2D H/H COSY NMR experiments where impurities of 0.05% signal intensity portion can be detected. Since the relaxation time can vary depending on the mixture and the solvent, theT1relaxation time...
Even if the impurities are all segregated into the nanopores, the maximum concentration is at most four times the impurity concentration in the bulk electrolyte. This would give rise to an estimated impurity concentration of 0.04 mol kg À 1, which is insignificant compared with the charge ...
solvent impurities. A tabulation of the 1 H and 13 C NMR data for all 48 impurities in order of chemical shift is included in the Supporting Information to aid in the assignment of unknown peaks. All of the compounds in Table 1 were obtained as single isomers. However, some solvents used...
The majority of the chemical shift changes are in the fast exchange regime on the NMR time scale, as observed by single weighted-average peaks containing information on the ligand-bound and ligand-free ratio. Thus, neither of these options could be exploited. Similarly, due to an elevated off...
Solvent, reference, and impurity peaks were removed prior to open to the public Digital resolutions for the most of the spectra were 0.0625 Hz, 0.125 Hz, and 0.0625 Hz for the FX-90Q, GX-400, and AL-400, respectively. When peaks exist outside the standard spectral width, a wider ...
impurity detectionWe evaluate the possibilities and limits of HR MAS NMR to detect and quantify side products during solid-phase synthesis, using a model system where pyroglutamate and glutamate are coupled in a well defined ratio. Resins swollen in deuterated and protonated solvent are studied. Use...