Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful method to determine the structure of biomacromolecules and their complexes in solution. It allows determination of the dynamics of proteins, RNA, DNA, and their complexes at atomic resolution. Therefore, NMR spectroscopy can monitor the often...
In-cell nuclear magnetic resonance (NMR) is a method to provide the structural information of a target at an atomic level under physiological conditions and a full view of the conformational changes of a protein caused by ligand binding, post-translational modifications or protein–protein...
The applications of 7Li NMR spectroscopy and imaging in biology and experimental medicine have been progressing steadily. The interest derives primarily from the clinical use of Li salts to treat mania and manic-depressive illness. One area of investigation is ionic transport across the cellular membr...
Applications to protein... JH Prestegard,AI Kishore - 《Current Opinion in Chemical Biology》 被引量: 140发表: 2001年 Recent Advances in Solution NMR: Fast Methods and Heteronuclear Direct Detection Today, NMR spectroscopy is the technique of choice to investigate molecular structure, dynamics, and...
systems of biological interest, phosphorus-31 NMR investigations of enzyme systems, the principles and state-of-the-art advances in the use of oxygen ... LJ Berliner,PM Robitaille - 《Cerebral Cortex》 被引量: 0发表: 1983年 15N‐NMR Spectroscopy—New Methods and Applications [New Analytical Me...
JL Griffin - 《Current Opinion in Chemical Biology》 被引量: 631发表: 2003年 Spectral Representation of Proton NMR Spectroscopy for the Pattern Recognition of Complex Materials Validation of multivariate models is of current importance for a wide range of chemical applications. Although important, it...
Applications involving a large number of different bio... Kay,E Lewis - 《Biochemistry & Cell Biology》 被引量: 320发表: 1998年 Deciphering Protein Dynamics from NMR Data Using Explicit Structure Sampling and Selection Perhaps one of the most prominent realizations of recent years is the critical...
This chapter highlights calcium and magnesium nuclear magnetic resonance (NMR) in chemistry and biology. NMR has become a very useful tool in the study of several metal ions, but the preferential interest in studies of ions, such as Li +2 , Co 2+ ,and Mn 2+7 indicates that one has ...
Biomedical applications of 10B and 11B NMR 来自 国家科技图书文献中心 喜欢 0 阅读量: 43 作者: P Bendel 摘要: This review focuses mainly on the detection and investigation of molecules used for boron neutron capture therapy (BNCT) by 10 B and 11 B NMR. In this binary radiation treatment, ...
Numerous ligand or protein-observe experiments exist that yield binding affinities, kinetics and the site of interaction from a single sample (in favourable cases). Even though this area of biomolecular NMR is relatively mature and has been reviewed extensively [32], new approaches and applications ...