随访终点时,NMOSD-ON ATAbs阳性组较阴性组患病眼预后差比例高(65.62%比36.36%,P<0.05),患病眼为复发眼,患病时最差视力<0.1为视力预后差的风险因素〔OR(95%CI)分别为8.56(2.15~36.45),18.32(3.25~103.22),均P<0.05〕;抗核抗体阳性,累及视交叉为NMOSD-ON复发的风险因素〔OR(95%CI)分别为22.98(1.79~295.35)...
aNovelty & Special Use>>Traditional Chinese Clothing>>Cheongsams 新奇&特别Use>>Traditional汉语Clothing>>Cheongsams[translate] aEfficacy and Safety Study as Add-on Therapy of SA237 to Treat NMO and NMOSD 效力和安全研究作为对待NMO和NMOSD的SA237添加疗法[translate]...
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The treatment was superior in preventing on-trial relapse in both the monotherapy and immunosuppressive therapy groups compared with placebo in the CHAMPION-NMOSD trial. Michael Levy, MD, PhD In a prespecified analysis of the CHAMPION-NMOSD (NCT04201262) open-label, phase 3 study, findings disp...
随着全球新型冠状病毒疫苗(简称新冠疫苗)密集地开发和获批,国内外正积极推动疫苗接种,以尽早建立群体免疫屏障[4]。与此同时,多发性硬化(multiple sclerosis,MS)及视神经脊髓炎谱系疾病(neuromyelitis optica spectrum disorders,NMOSD)患者接种新冠疫苗的安全性和有效性,逐渐引起关注。主要问题集中在: ...
Intra-retinal layer thickness in NMOSD-ON eyes with and without microcystic macular edema.Elisa, SchneiderHanna, ZimmermannTimm, OberwahrenbrockFalko, KaufholdElla, Maria KadasAxel, PetzoldFrieder, BilgerNadja, BorisowSven, JariusBrigitte, Wildemann...
A key focus is on differentiating NMOSD from MS and from myelin oligodendrocyte glycoprotein antibody-associated encephalomyelitis (MOG-EM; also termed MOG antibody-associated disease, MOGAD), which shares significant similarity with NMOSD with regard to clinical and, partly, ...
These new drugs may potentially substitute rituximab and classical immunosuppressive therapies, which were as yet the mainstay of treatment for both, AQP4-IgG-positive and -negative NMOSD. Here, the Neuromyelitis Optica Study Group (NEMOS) provides an overview of the current state o...
Neuromyelitis Optica Spectrum Disorders (NMOSD), Its Effects on Pregnancy and the Effects of Pregnancy on NMOSD. A Mini-Reviewdoi:10.4103/neurol-india.Neurol-India-D-23-00647Reshma S. ShaikDepartment of Neurology, Nizam’s Institute of Medical Sciences, Hyderabad, Telangana, IndiaSireesha Yareeda...
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