NLRP3 is required for complement-mediated caspase-1 and il-1beta activation in ICH. J Mol Neurosci 2017; 61(3): 385-395.NLRP3is required for complement-mediated caspase-1and IL-1beta activation in ICH. Yao ST,Cao F,Chen JL,et al. Journal of Molecular Neuroscience . 2017...
depression; electroacupuncture; P2X7R/NLRP3/IL-1β; liver-brain axis; chronic unpredictable mild stress (CUMS); behavior; rat; Baihui (GV20); Yintang (GV29); Ganshu (BL18)1. Introduction Depressive disorder is a crippling condition that substantially affects psychosocial functioning and reduces ...
THE ATTENUATION OF IL‐1BETA RESPONSE IN MAC‐LD IS DUE TO BOTH DECREASES OF NLRP3 INFLAMMASOME AND TLR2 ACTIVATIONinflammasomeactivation pathwaytranscription pathwaymacrophageMycobacterium avium complexdoi:10.1111/resp.13207_30NoneJohn Wiley & Sons, LtdRespirology...
a抑制后能够减少高糖所致肾小管上皮细胞的损伤,其机制可能与NLRP3、ASC、及IL-1β的活化密切相关。 After the suppression can reduce the high sugar result tubulus renalis epithelial cell the damage, its mechanism possible and NLRP3, ASC, and IL-1β activation close correlation.[translate]...
Caspase-1, but not ASC or NLRP3 inflammasome components, mediates IL-1beta activation and antifungal defense in disseminated candidiasisRituximabTh17Mass spectrometry is becoming a more and more powerful tool for investigating protein complexes. Recent developments, based on different ionization techniques,...
Provoost S, Maes T, Pauwels NS, Vanden Berghe T, Vandenabeele P, Lambrecht BN, et al. NLRP3/caspase-1-independent IL-1beta production mediates diesel exhaust particle-induced pulmonary inflammation. J Immunol 2011;187:3331-7.Provoost S, Maes T, Pauwels NS, Vanden Berghe T, Vandenabeele...
The correlation between the degeneration scores and expression levels of NLRP3, caspase-1, and IL-1 beta were also analyzed. The mRNA expression levels of the three molecules (NLRP3, caspase-1, and IL-1 beta) were higher in the degenerate IVDs group than the controls (nondegenerate IVDs ...
Relationship of NLRP3 inflammasome in blood, IL-1 beta and il-18 cytokine level with cognition in OCDnder, BetülOktay, Melike TetikDirek, NeeAyka, CansuEkinci, BurcuYara, TutkuKuruolu, AykutErmi, aatayOktay, YavuzAlkn, TunAnatomy: International Journal of Experimental & Clinical Anatomy...
NLRP3 inflammasome activationIL-1 betaMacrophageDamage associated molecular patterns (DAMPs) are released form red blood cells (RBCs) during intravascular hemolysis (IVH). Extracellular heme, with its pro-oxidant, pro-inflammatory and cytotoxic effects, is sensed by innate immune cells through pattern ...
NLRP3 inflammasomeIL-1 betaNF-kappa B/P65Caspase-1The NLRP3 inflammasome rapidly responds to many infections and stress signals and is involved in the pathogenesis of numerous inflammatory disease processes. Tannic acid plays a role in antioxidant, antifungal and antitumor activities. Here, we ...