CAR-NKT cell therapy: a new promising paradigm of cancer immunotherapy Kaveh Hadiloo Safa Tahmasebi Abdolreza Esmaeilzadeh Cancer Cell International (2023) Markers and makers of NKT17 cells Nurcin Liman Jung-Hyun Park Experimental & Molecular Medicine (2023) Invariant natural killer T cells ...
Unlike HSA low NKT cell subsets, HSA high NKT cell precursors are not accurately identified by flow cytometry because of their extreme rarity. Here, we describe an NKT cell enrichment strategy to identify unambiguously NKT cell precursors at the HSA high stage that can be used to assess their ...
Ripk3 À / À mice, as demonstrated by the reduction in inflamma- tory cell infiltrates and apoptotic cells (Fig. 4b,c). Other inflammatory markers significantly reduced in the Ripk3 À / À mice included IFN-g and TNF protein levels in the serum and mRNA levels in the liver, ...
Immuno-phenotyping by flow cytometry was done using markers for NKT-cells (CD3 and CD56), stimulatory KIRs (KIR2DL4, CD158D) and inhibitory KIRs (KIR3DL1, CD158E1). Absolute counts and percentage of NKT cells expressing CD158D and CD158E1 together with their mean fluorescence intensity (...
The CD26 molecule (dipeptidyl peptidase IV, DPP IV, EC 3.4.14.5) is a broadly expressed multifunctional transmembrane glycoprotein involved in different biological processes through its proteolytic activity as well as its role in T-cell activation. Based on recent findings, immunological abnormalities ...
Of all the B cell-markers evaluated among paired samples, a higher expression of MZB cells at day 8 of cycle 1 has resulted in enhanced PFS in PVd treated patients. Within T cells, pomalidomide treatment did not decrease the frequency of CD8 T cells when compared with screening samples. ...
d, e Activated T-cell and NK cell markers were examined on C D8+NKT-like cells, NK cells, and NK1.1−CTLs by flow cytometry. Black lines show isotype controls, while red lines show the expression intensities of indicated markers. Flow cytometry experiment was repeated thrice 1311 ...
For this purpose DX5+NKT cells were isolated from spleen and liver and several T and NK cell surface markers as well as maturation and activation markers were studied by flow cytometry. Distinct differences could be found between both subsets and between mouse strains....
CD3+CD56+ NKT cell subsets are a minor T cell subset in peripheral blood and conduct the killing of tumor cells in direct manner. Little is obvious about levels and surface markers of these cells such as NKG2D in different cancers, especially in CRC. METHODS: We included 15 non-metastatic ...
(PMA)plus ionomycin.Then flow cytometry was employed to detect the expression of cell surface markers (CD3,CD56,CD4,and CD8)and the production of IL -4and IFN -γ.The frequency ofCD3+CD56+NKT cells in PBMCs was (6.39±2.34)%,in which TCRV α24+was 1.5%,TCRV β11+positive was 1.2...