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KCNH2 is also known as the human-ether-a-go-go-related gene (HERG), so-named because the mutation in the Drosophila fruit fly caused it to shake like a go-go dancer. The current generated by HERG channels shows unusual voltage dependence. In contrast to IKs, IKr activates relatively ...
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J. Immunol. 177, 7303–7311 (2006). Article CAS Google Scholar Martinez, F. O. et al. Genetic programs expressed in resting and IL-4 alternatively ...
GC ID, gene card ID; FA, fatty acid; ETC, electron transport chain; Pyr., pyruvate; AA, amino acid. Previous studies were utilized to compile a list of target genes potentially regulated by PGC-1α in NK cells. Genes from studies using different cell types and metabolic stresses were con...
In a host (e.g., IL-10-/- or NOD2/CARD15 or TLR polymorphisms) that is deficient in the regulation of tolerance, inactive dendritic cells (iDC) mature and aid in the differentiation of precursor T helper cells (pT) to Th1 cells. These Th1 cells express CXCR3, TNF-α, and IFN-γ...
Corazza N, Eichenberger S, Eugster HP, Mueller C: Nonlymphocyte-derived tumor necrosis factor is required for induction of colitis in recombination activating gene (RAG)2(-/-) mice upon transfer of CD4(+)CD45RB(hi) T cells. J Exp Med. 1999, 190: 1479-91. 10.1084/jem.190.10.1479. Arti...