Seventy timed-pregnant Sprague-Dawley rats were exposed to either air (control) or 75% nitrous oxide (N 2 O) for 24 hours on day 8 of gestation. Four rats from each group were killed on days 11-16, 18, and 20, and laparotomy was performed. The viability of the embryos/fetuses was ...
Please try refreshing the page. If that doesn't work, please contact support so we can address the problem. Abstract Adverse effects may occur when patients with air in the pleural space or in the cerebral ventricles breathe nitrous oxide. We developed an animal model to learn whether similar...
Nitrous oxide has little or no effect on body temperature, metabolism, blood pressure, volume, or composition, or on the genitourinary system. Diaphoresis, increased muscle tone, or both may occur with induction of anesthesia with nitrous oxide. ...
N2O, a flammable, anesthetic and analgesic gas, used in both general and outpatient dental anesthesia. Its use has been associated with miscarriage, organ injuries, and dependence and abuse, although the data linking nitrous oxide to these problems are controversial. The informal name of nitrous ox...
Body weight gain was measured on the day before castration, at 3 d postcastration, and at weaning. Data were analyzed using a mixed model in SAS (Cary, NC). Nitrous oxide successfully induced anesthesia in all N(2)O piglets, as validated by a skin pinch test and the loss of the ...
Summary Nitrous oxide (N2O) has been used as an anaesthetic agent since 1844. It has two well recognized adverse effects: it oxidizes Co(I) to Co(II) and so inactivates vitamin B12, and its high partial pressure in blood allows it to expand into cavities in the body such as the ...
Toxicity and irritant effects of nitrous oxidein humans are very low. It is an anesthetic.Inhalation of this gas at high concentrationscan produce depression of the central nervous system, decrease in body temperature,and fall in blood pressure. The LC50 valueof a 4-hour exposure in mice is ...
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In the State of California, theintentto inhale is a misdemeanor: 381b. Any person who possesses nitrous oxide or any substance containing nitrous oxide, with the intent to breathe, inhale, or ingest for the purpose of causing a condition of intoxication, elation, euphoria, dizziness, stupefactio...
Abstract Oxidative stress results from the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in quantities exceeding the potential activity of the body’s antioxidant system and is one of the risk factors for the development of vascular dysfunction in diabetes and exposu...