IV nitroglycerin has been used in the management of acutely decompensated (e.g., congestive) heart failure and other low cardiac-output states† [off-label].Current guidelines recommend a combination of drug therapies (e.g., ACE inhibitors, angiotensin II receptor antagonists, angiotensin receptor...
Nitroglycerin drug interactions (more detail)Nitroglycerin (Topical) PharmacokineticsAbsorptionBioavailabilityMean absolute bioavailability approximately 50% of a 0.75-mg dose applied to the anal canal as nitroglycerin 0.2% ointment (not commercially available in US)....
between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy...
Drug interactions Potentially hazardous interactions with other drugs Anticoagulants: infusion of GTN reduces anticoagulant effect of heparins. Antidepressants: tricyclics may reduce effect of sublingual tablets due to dry mouth. Antimuscarinics: may reduce effect of sublingual tablets due to dry mouth....
BCS Class1 FDA 21 CFR250.102 CAS DataBase Reference55-63-0(CAS DataBase Reference) EWG's Food Scores2-6 FDA UNIIG59M7S0WS3 NCI Dictionary of Cancer Termsnitroglycerin NCI Drug Dictionarynitroglycerin show more Safety Symbol(GHS) Signal wordDanger ...
Daily headaches sometimes accompany treatment with nitroglycerin. In patients who get these headaches, the headaches may be a marker of the activity of the drug. Patients should resist the temptation to avoid headaches by altering the schedule of their treatment with nitroglycerin, since loss of head...
关键词: Humans Nitroglycerin Sulfhydryl Compounds Cysteine Neurotransmitter Agents Blood Volume Drug Tolerance DOI: 10.1016/S0735-1097(10)80343-2 被引量: 86 年份: 1990 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 全文购买 Elsevier (全网免费下载) Elsevier Semantic Scholar 万方医学 dx....
Nitroglycerin drug usage statistics for the United States (2013 - 2022). Statistics include drug synonyms and therapeutic classes, including: Nitroglycerin, Gonitro, Minitran, Nitro IV, Nitro-bid, Nitro-dur, Nitroglycerin IN Dextrose 5%, Nitrol, Nitrolin
However, the drug is poorly soluble in water (solubility is about 1 mg/ml). Decreased potency of nitroglycerin sublingual tablets is mainly due to evaporation of nitroglycerin from the tablets (Fig. 6.2). Sign in to download full-size image Figure 6.2. Content uniformity for conventional ...
Classification Code: Cardiovascular Agents; Drug / Therapeutic Agent; Explosive Agents; Human Data; Mutation data; Reproductive Effect; Skin / Eye Irritant; Tumor data; Vasodilator [coronary]; Vasodilator agents Index of Refraction: 1.488 Molar Refractivity: 39.2 cm3 Molar Volume: 135.8 cm3 Surf...