acid phase followed by extraction of the ketone. Previously the reaction has found only limited application because of the low yields obtd. when an alpha H atom is present. As a result of the presence of the salt the yield is increased by >=50%.MAURICE CHASTRETTE, ROGER AMOUROUX ET ...
So, somehow, I need to have an alcohol on benzene and somehow I need to create a carboxylic acid in some way. Alright. So remember, if we think backwards in terms of this and we cut this bond, what we had at one point is we had this alcohol and we had this carboxylic ...
über eine von 1,4-Dihalogenbutan abgeleiteten Grignard-Reagenzaddition an Lactone. Unter den besten Verfahren zur Synthese von funktionalisierten Cyclopentyl-, Cyclopentenyl- oder Cyclopentylidenalkanen stellt sich die Cyclopentadienylanionaddition an eine Carbonylgruppe heraus, gefolgt von einer ...
wherein the fragrance present in addition to the nitrile compound comprises at least one member selected from the group consisting of a hydrocarbon, an alcohol, a phenol, an aldehyde, a ketone, an acetal, an ether, an ester, a carbonate, a lactone, an oxime...
Incorporation of nitrile groups into fine chemicals is of particular interest through C(sp3)–H bonds activation of alkyl nitriles in the synthetic chemistry due to the highly efficient atom economy. However, the direct α-functionalization of alkyl nitriles is usually limited to its enolate chemist...
acid phase followed by extraction of the ketone. Previously the reaction has found only limited application because of the low yields obtd. when an alpha H atom is present. As a result of the presence of the salt the yield is increased by >=50%....
A-seco-triterpenoids with a methylketone group were synthesized from epimeric 3-hydroxy-3-methyl-1-cyano-2,3-seco-triterpenoids of the lupane and 19 β ,28-epoxy-18 αH -oleanane types, which were formed by a Grignard reaction. The resulting methylketones underwent under base-catalysis ...
Examples of previous phthalonitrile monomers and polymers demonstrate the versatility and importance of this growing class of materials. Keller, in the U.S. Pat. No. 4,234,712, used sulphone and ketone groups to link phthalocyanines, thus forming high temperature structural composites and adhesives...
The rapid exchange allows in situ alkylations with aldehyde, ketone and acyl cyanide electrophiles without prior Grignard addition (Section II-4). Furthermore the exchange uses rapid equilibration allowing the diastereoselective alkylation of diastereomeric alpha-bromonitriles....