Fig 3.Henipavirus structure and genome organization and models of the G and F glycoprotein soluble ectodomains, Hendra virus (HeV-sG) and Nipah virus (NiV-sF), respectively, and their complexes with respective NiV and HeV cross-reactive neutralizing monoclonal antibodies m102.3 (anti-G) and 5B...
尼帕病毒(Nipah Virus,简称NiV),属于副黏病毒科,是一种包膜多形病毒,具有螺旋对称性。病毒的基因组由大约18.2kb长的非分段的单股负链RNA组成,编码六种蛋白:核衣壳(N)、磷蛋白(P)、基质蛋白(M)、融合蛋白(F)、糖蛋白(G)和RNA聚合酶(L)。N、P和L以及病毒RNA形成核糖核蛋白复合物,这是一种调节转录和病毒R...
尼帕病毒(Nipah Virus,简称NiV),属于副黏病毒科,是一种包膜多形病毒,具有螺旋对称性。病毒的基因组由大约18.2kb长的非分段的单股负链RNA组成,编码六种蛋白:核衣壳(N)、磷蛋白(P)、基质蛋白(M)、融合蛋白(F)、糖蛋白(G)和RNA聚合酶(L)。N、P和L以及病毒RNA形成核糖核蛋白复合物,这是一种调节转录和病毒R...
Re-emergence of Nipah virus outbreak in Kerala, India: a global health concerndoi:10.1080/23744235.2024.2334853Prakasini SatapathyMahalaqua Nazli KhatibShilpa GaidhaneQuazi Syed ZahiruddinSarvesh RustagiNeelima KukretiRachana MehtaRanjit SahInfectious Diseases...
The Nipah virus (NiV), a member of the Paramyxoviridae family, is notorious for its high fatality rate in humans. The RNA polymerase machinery of NiV, comprising the large protein L and the phosphoprotein P, is essential for viral replication. This study
Nipah virus (NiV) outbreaks in the global south have amped development of therapeutics against the fatal and potentially pandemic-causing virus. Herein, th
Dr. In-Kyu Yoon, acting executive director of vaccine research & development at CEPI, funders of the trial and one of the leading global funders of Nipah virus research, said, "Nipah has epidemic potential, with its fruit bat hosts found in areas home to over two billion people. This tri...
Nipah virus (NiV) is a non-segmented, negative-strand (NNS) RNA virus, belonging to Paramyxoviridae. The RNA polymerase complex, composed of large (L) protein and tetrameric phosphoprotein (P), is responsible for genome transcription and replication by catalyzing NTP polymerization, mRNA capping ...
Nipah virus (NiV) is a highly lethal zoonotic paramyxovirus that poses a severe threat to humans due to its high morbidity and the lack of viable countermeasures. Vaccines are the most crucial defense against NiV infections. Here, a recombinant chimpanze
Nipah virus (NiV) is a zoonotic pathogen with high mortality rates, posing significant public health threats in South and Southeast Asia. Traditional outbreak prediction models often fall short in handling the complexities and uncertainties inherent in epidemiological data. This research introduces a nove...