药店国别:无产地国家:德国处方药:是所属类别:150毫克 60软胶囊/盒包装规格:150毫克 60软胶囊/盒计价单位:盒生产厂家中文参考译名:无生产厂家英文名:Boehringer Ingelheim原产地英文商品名:Vargatef Soft Capsules 150mg 60Caps/box原产地英文药品名:nintedanib中文参考商品译名:Vargatef软胶囊 150毫克 60软胶囊/盒中文...
Commercially, nintedanib is available as soft gelatin capsules for treatment against idiopathic pulmonary fibrosis. Since it has very low oral bioavailability (4.7%), high doses of a drug, such as 100鈥 150mg, are administered, which can cause problems of gastrointestinal irritation and ...
The above defined capsules may be packaged in a suitable glass container or flexible plastic container, or in an aluminium pouch or double poly bag. The following examples of carrier systems (formulations), soft gelatin capsules, bulk packaging materials, and of a manufacturing process are illustrat...
Suitable preparations for administering the active pharmaceutical ingredients of the present invention will be apparent to those with ordinary skill in the art and include for example tablets, pills, capsules, suppositories, lozenges, troches, solutions, syrups, elixirs, sachets, injectables, inhalative...
Nintedanib reached maximum plasma concentrations approximately 2 to 4 hours after oral administration as a soft gelatin capsule under fed conditions. The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers. Absorption and bioavailability are decreased by...
OFEV are soft gelatin capsules containing 100 mg or 150 mg nintedanib (as nintedanib esilate) for oral administration. Excipients: Each OFEV capsule contains medium-chain triglycerides, hard fat and lecithin. Uses Nintedanib Esylate is the salt form of Nintedanib, which is angiokinase inhibitor ...
The present invention relates to an oral suspension of 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)- methylcarbonyl)-N-methyl-amino)-anilino)-1-pheny1-methylene]-6-methoxycarbonyl-2- indolinone-monoethanesulphonate adapted for encapsulation in soft gelatin capsules.JADHAV, BHUSHAN...
Nintedanib reached maximum plasma concentrations approximately 2 to 4 hours after oral administration as a soft gelatin capsule under fed conditions. The absolute bioavailability of a 100 mg dose was 4.7% (90% CI: 3.62 to 6.08) in healthy volunteers. Absorption and bioavailability are decreased by...