Nimesulide is available in various formulations, including tablets, suspensions, and topical gels, and is generally well-tolerated when used as directed. However, it is important to note that like other NSAIDs, nimesulide may have potential side effects, such as gastrointestinal disturbances and ...
However, long-term uses of non-selective NSAIDs can lead to gastrointestinal toxicity from sustained inhibition COX-1. But one can overcome such problem by formulating them as colon specific delivery. In the light of this information, the present study was carried out to develop oral colon ...
Water-soluble nimesulide salt comprised of the product obtained from the reaction of nimesulide and L-lysine, preparation thereof, aqueous solution containing it, associations based on nimesulide with cyclodextrins, and uses thereof. J Geczy,B Pirotte,G Piel,... 被引量: 26发表: 1995年 INCLUSION ...