NIH Genetic and Rare Diseases Information Center (GARD)orphan drugsOrphanetrare diseasesThis column profiles three important online resources for rare disorder information. The National Organization for Rare Disorders (NORD) Rare Disease Database set the standard for thorough, detailed monographs on rare ...
转化医学:NIH花费数千万美元支持9个废弃药物改造项目 美国国立卫生研究院(NIH)近日声明了在废弃药物新用途的竞争中胜出的科研人员和医药公司,它们将获取每年总经费达1280万美元的9个项目,这表明:刚成立仅19个月的国家转化医学推进中心(NCATS)实现了利用新方法加快药物研发这一目标,NCATS官员如此地说。 国家转化医学推...
In 2007, the US National Institutes of Health (NIH) introduced the Genome-Wide Association Studies (GWAS) Policy and the database of Genotypes and Phenotypes (dbGaP) to facilitate 'controlled' access to GWAS data based on participants' informed consent. dbGaP has provided 2,221 investigators acce...
“Our findings solve a longstanding puzzle in RPE65’s structure, clarifying its function, while expanding our knowledge of membrane-binding in a way that we hope will inform disease models in more accurate ways,” investigators concluded. References 1 Sheetal Uppal, Tingting Liu, Emily Galvan,...
According to National Institutes of Health/National Eye Institute researchers, the study may help lead to gene therapy for rare inherited blinding disease. A cross section of the stem-cell generated RPE is shown after it has been fed photoreceptor outer segments. Arrows point to lipid deposits ...
Rare, incurable conditions call for the most innovative treatments—and that’s exactly the approach the National Institutes of Health is taking to develop a new test for patients with methylmalonic acidemia, or MMA...
The proposed policy would require that all NIH-funded clinical trials be registered in ClinicalTrials.gov and that summary results be posted to the database in a timely matter. Both documents are open for a 90-day public comment period, and comments will be taken into consideration before ...
profiles.onbase.com Home Create a new account or login. Creating an OnBase Profile is your first step toward accessing a wealth of information. Once your account is finalized, you can visit a suite of systems designed to let you share your points of view, receive training, download important...
Most recently, the Mount Sinai Acute GvHD International Consortium (MAGIC) has revisited these criteria based on a review of their extensive database containing detailed clinical information on aGvHD, and recommended more precise definitions for grade IV aGvHD [16]. Specifically, stage 4 cutaneous inv...
My bill provides $100 million in new funding to expand efforts to develop new antibiotics, create rapid diagnostic tests and build a national genome sequence database on all reported resistant human infections. Funding for the NIH lays the foundation for drug and device discoveries over the next ...