Pregnancy Category C: Nifedipine has been shown to produce teratogenic findings in rats and rabbits, including digital anomalies similar to those reported for phenytoin. Digital anomalies have been reported to occur with other members of the dihydropyridine class and are possibly a result of compromised...
PregnancyCategory C.LactationDistributed into milk. Discontinue nursing or the drug.Pediatric UseSafety and efficacy remain to be fully established in children; however, some experts have recommended dosages for hypertension based on clinical experience....
This medicine is not recommended during pregnancy and breastfeeding. It should not be understood to indicate that the use of Nifedipine is safe, appropriate, or effective for you. Always consult your health care professional before using this, or any other, drug. Related products Trazodone 25mg ...
Pregnancy category: C - Australia C - United States (Risk cannot be ruled out) Forms of active pharmaceutical ingredients (APIs): Nifedipine Base Chemical, international, and other names of this drug: 4-(2-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine ...
It should be avoided or used with caution during pregnancy, as it may cause harm to the fetus, although no definitive evidence exists to categorize it as a direct teratogen. Nifedipine should be stored in a cool, dry place, away from direct sunlight and heat sources. The ideal storage ...
You should not use nifedipine if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks.Before taking nifedipine, tell your doctor if you have kidney or liver disease, a blockage in your digestive tract (stomach or intestines), a history of ...
According to the inclusion criteria as defined in the study protocol, patients were excluded if they had a contraindication for nifedipine (as described in the approved prescribing information),11 including known hypersensitivity to nifedipine, pregnancy, breastfeeding, or CV shock. Concomitant ...
Pregnancy Category C Risk of Intrauterine Growth Retardation Avoid in Lactation XII. Metabolism Rapid and near complete absorption of sublingual (SL) route Highly Protein bound (98%) CYP3A4 metabolism to inactive metabolites Immediate Release Half Life: 3 hours Reduce dosing in hepatic dysfunction ...
According to the inclusion criteria as defined in the study protocol, patients were excluded if they had a contraindication for nifedipine (as described in the approved prescribing information),11 including known hypersensitivity to nifedipine, pregnancy, breastfeeding, or CV shock. Concomitant ...