Niemann-Pick C1-like protein (NPC1L1)In vitro and mouse studies suggest NPC1L1 inhibitors could help prevent HCV infection.doi:10.1038/scibx.2012.76Science Business Exchange
1.Niemann-pick protein C1(NPC1) is a large integral membrane glycoprotein that resides in late endosomes,whereas niemann-pick protein C2(NPC2) is a small soluble protein found in the lumen of lysosomes.然而,在C型尼曼-匹克病(N iemann-Pick d isease typeC,NPC)细胞中,胆固醇和糖鞘脂(glycos...
尼曼匹克C1前体蛋白抗体,Anti-NPC1/Niemann Pick C1可用于免疫组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC,BIO等,产品经无数次市场验证及客户反馈,质量稳定可靠。 产品别名: Niemann Pick C1; Niemann Pick C1 protein precursor; Niemann Pick disease, type C1; Niemann-Pick C1 protein; NPC; NPC1; ...
然而,在C型尼曼-匹克病(N iemann-Pick d isease typeC,NPC)细胞中,胆固醇和糖鞘脂(glycosphingolip-ids,GSL)聚集在LE/LY中,这些物质从LE/LY转运到细胞内其它细胞器的速度非常缓慢,其原因在于NPC细胞中C型尼曼-匹克蛋白1(N iemann-pick protein C1,NPC1)或C型尼曼-匹克蛋白2(N iemann-pick protein C2...
世联博研公司现货供应MYBIOSOURCE INC.品牌订货号为MBS9379670的Plant Niemann Pick C1 Like Protein 1 (NPC1L1) ELISA Kit from MYBIOSOURCE INC.产品
Chen KJ, Jin RM, Shi CC, Ge RL, Hu L, Zou QF, Cai QY, Jin GZ, Wang K. The prognostic value of Niemann-Pick C1-like protein 1 and Niemann-Pick disease type C2 in hepatocellular carcinoma. Journal of Cancer. 2018:9(3):556-563. doi: 10.7150/jca.19996. Epub 2018 Jan 1[PubMed...
Niemann–Pick disease has been associated with mutations in three different genes: sphingomyelin phosphodiesterase 1 (SMPD1), Niemann–Pick C1 (NPC1), and Niemann–Pick C2 gene (NPC2) (seeTable 58.2). ● Mutations ofSMPD1are most prevalent in Ashkenazi Jews, with three mutations—R496L, ...
Niemann-Pick C1 Pathophysiology Associates with Different Classes of Protein Trafficking Phenotypes Elicited by NPC-1 MutationsNiemann-Pick Type C disease (NP-C) is caused by a defect in the trafficking of endocytosed cholesterol with sequestration of cholesterol in lysosomes and late endosomes. Over ...
Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2 Niemann-Pick C1-like 1 (NPC1L1) is an essential intestinal component of cholesterol absorption. However, little is known about the molecular regulation of ... WA Alrefai,...
Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol Absorption Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Murine model of Niemann-Pick C disease: Mutation in a cholesterol homeostasis gene