nicotinic词组 nicotinic acid[生化]烟酸;尼克酸;烟碱酸nicotinic词源中文解释 "与尼古丁有关的",1873年,来自 nicotine + -ic。另一种 nicotic 的说法可以追溯到1847年。nicotinic_医学行业词汇 烟碱的:指烟碱和其他药物的一种作用,开始时兴奋,后来(高剂量时)抑制自主神经节处与神经肌肉接头处的神经冲动nicotinic...
The presence of nicotine and nicotinic acid (NA) in the marine environment has caused great harm to human health and the natural environment. Therefore, there is an urgent need to use efficient and economical methods to remove such pollutants from the environment. In this study, a nicotine and...
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Cardiovascular toxicity of nicotine: implications for nicotine replacement therapy. J Am Coll Cardiol 29: 1422–1431. Bird ED, Spokes EG, Barnes J, MacKay AV, Iversen LL, Shepherd M (1977). Increased brain dopamine and reduced glutamic acid decarboxylase and choline acetyl transferase activity in...
Alzheimer’s disease (AD) is the most common form of dementia among older persons. Pathognomonic hallmarks of the disease include the development of amyloid senile plaques and deposits of neurofibrillary tangles. These changes occur in the brain long before the clinical manifestations of AD (cogniti...
Acute effects of smoking during modified sham feeding in duodenal ulcer patients: An analysis of nicotine acid secretion, gastrin, catecholamines, epidermal growth factor, prostaglandin E2, and bile acids. Scand J Gastroenterol 28: 487–494. Article CAS PubMed Google Scholar Lindenboim L, Pinkas...
This peptide (RVG-P) is the same length as SCoV2P (30-mer), similar amino acid composition and has high sequence homology in the neurotoxin domain (Table S1). Functionally, the RVG-P, unlike SCoV2P, did not potentiate α7 nAChR ACh-mediated responses at low concentrations (Fig. S5). ...
(NaCl 128 mM; KCl 2.4 mM; CaCl23.2 mM; MgSO41.2 mM; HEPES 25 mM; glucose 10 mM; ascorbic acid 1 mM; pargyline 1 mM; pH=7.5), and the protein was measured using the Lowry assay. Uptake was initiated by the addition of [3H]dopamine (final concentration 0.075...
Single-molecule imaging of a fluorescent unnatural amino acid incorporated into nicotinic receptors. Biophysical J 2009; 96: 226–37. 16 Harkness PC, Millar NS. Changes in conformation and subcellular distribution of α4β2 nicotinic acetylcholine receptors revealed by chronic nicotine treatment and ...
5857Accesses 36Altmetric Metrics Abstract Binding of the neurotransmitter acetylcholine to its receptors on muscle fibers depolarizes the membrane and thereby triggers muscle contraction. We sought to understand at the level of three-dimensional structure how agonists and antagonists alter nicotinic acetylcho...