The article highlights the need for more research to understand the effects of e-cigarettes on the brain and peripheral organs, as well as the long-term genetic modifications they may cause. It also explores the connection between e-cigarette use and subsequent drug i...
The deleterious effects of nicotine are not restricted to adulthood, as nicotinic acetylcholine receptors regulate critical aspects of neural development. However, the exact mechanisms underlying the particular sensitivity of women to develop tobacco dependence have not been well elucidated. In this mini-...
Nicotine was reported to have pro-cognitive effects in humans and animals. However, high doses of nicotine are harmful for many organs.The aim of the study was to check whether a 30-day exposure to transdermal nicotine affects memory and biochemical parameters in mice.A total of 32 mice (...
Nicotine binds itself to specific receptors and triggers the release of dopamine, which boosts attention but could also cause reward-seeking behavior. Nicotine has short-term pharmacological effects, including increased heart rate and blood pressure. ...
which is associated with increased glucose metabolism in the heart and other organs (Fig.6). Nicotine has been seen to reduce systemic inflammation, partially alleviating age-related hypermetabolism, and also has systemic anti-aging effects by increasing NAD+levels, which remodels glucose metabolic ...
Interacting rather with the drug in the blood than with a receptor in the brain, the vaccines are in addition free of side effects due to central interaction. For drugs like nicotine interacting with different types of receptors in many organs, this is a further advantage. There are three ...
We followed an organ-based systematic approach to decipher the effect of nicotine in damaged organs corresponding to COVID-19 pathogenesis (12 related diseases). Considering that the effects of nicotine and cigarette smoke are different from each other, it is necessary to be careful in generalizing...
The pharmacological effects of nicotine are very diffuse and affect all major organs of the body wherever there are nicotinic cholinergic receptors. Abood and colleagues have pointed out that there are actions of nicotine unrelated to cholinergic receptors [34]. Nevertheless, most actions of nicotine...
Secondly, as it has been demonstrated that APN receptor (AdipoR) phosphorylation may involve in the regulation of APN sensitivity in multiple organs24, and AdipoR1 is abundantly expressed in endothelial cells; therefore, we further investigated the expression of AdipoR1 in aortic tissue. As illustrat...
Interacting rather with the drug in the blood than with a receptor in the brain, the vaccines are in addition free of side effects due to central interaction. For drugs like nicotine interacting with different types of receptors in many organs, this is a further advantage. There are three ...