Nicotine contributes to the pathogenesis of a wide range of cancers including breast cancer through its carcinogens such as (4-methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N-nitrosonornicotine (NNN). Current study aims to review the mechanistic function of nicotine in the initiation, ...
in breast cancer patients. We found thatLCN2expression was negatively correlated withERα, PR, andHER2expression (Supplementary Fig.12C). To further clarify the role of LCN2 in inducing epithelial phenotype, we treated cancer cells (MDAMB231, MCF10CA1a) with human recombinant LCN2 (hrLCN2)....
二、 语法填空模考精选(已排除全段/跨段题):1. Smoking speeds up aging because nicotine contributes to your blood vessel becoming narrower, (26)decreases blood flow to your face and makes it wrinkle prematurely.2. Van Gogh painted Olive Trees in 1889, the year after his falling out with his...
Molecular Mechanisms of Nicotine-induced Bladder Cancer Cigarette smoke is a major risk factor for bladder cancer and contributes to chemoresistance in bladder cancer patients who continue to smoke while receivi... RJ Chen,YS Ho,CH Wu,... - 《Journal of Experimental & Clinical Medicine》 被引量...
摘要: Nicotine contributes to Staphylococcus aureus-induced osteomyelitis.Nicotine induces the Nrf2/Slc7a11 signaling axis and influences osteomyelitis.Erastin can mitigate nicotine's effects via glutamate/glutathione metabolism.关键词: Nicotine Osteomyelitis Macrophage Nrf2/Slc7a11 signaling axis Glutamate/...
In addition, a large number of AA women who are obese and develop aggressive form of breast cancer also smoke [32]. Mechanisms by which smoking contributes to the development of this aggressive disease in obese AA women remains poorly understood. In this study, we used immune-deficient nude ...
Which of the following is a cancer causing agent? View Solution Exams IIT JEE NEET UP Board Bihar Board CBSE Free Textbook Solutions KC Sinha Solutions for Maths Cengage Solutions for Maths DC Pandey Solutions for Physics HC Verma Solutions for Physics ...
In addition, we find nicotine signaling also inhibits the interaction of YAP1 with P63, which contributes to the inhibitory effect of nicotine on apoptosis. Using immunohistochemistry analysis we observed upregulation of YAP1 in a significant portion of esophageal cancer samples. Consistently, we have...
Our results revealed a novel mechanistic insight on how chronic nicotine exposure contributes to worse clinical outcome of metastatic lung cancer and implicated the risk of using nicotine gateway for smoking cessation in cancer patients.Similar content being viewed by others Nicotine promotes breast ...
Exposure to cigarette smoke significantly enhances susceptibility to bacterial infections by inducing physiological and structural alterations, including i