Nicotine is an alkaloid derived from tobacco leaves that, when inhaled through smoking or absorbed through chewing tobacco, acts on the brain by stimulating certain receptors, resulting in the release of dopamine and norepinephrine. It is involved in reward pathways and plays a major role in the ...
Nicotine is the major addictive component of tobacco smoke, and nicotine acts in the brain by stimulating proteins called nicotinic acetylcholine receptors (nAChRs). These nAChRs are made up of different types of subunits, one of which is the α5 subunit—the focus of the new study. In their ...
A toxic alkaloid, C10H14N2, that is found in the tobacco plant, constitutes the primary addictive substance in tobacco products, and acts as a stimulant at low doses. [French, from New Latinnicotiāna,nicotiana; seenicotiana.] American Heritage® Dictionary of the English Language, Fifth Edit...
It's very easily affected by nicotine, research shows. This is especially true for young people, because this part of the brain doesn't finish developing until about age 25. Nicotine acts like a key to unlocking special receptor(感受器)molecules on the outside of cells in the brain, ...
Nicotine acts as both asedative and a stimulant, producing temporarily pleasant physical and mood-altering effects in the brain. Nicotine increases heart rate and alertness, produces euphoria, and makes users feel more relaxed. These effects can make the user want to continue using tobacco products...
Nicotine acts in a dose-dependent manner (EC 50 =4M) to elicit Ca 2+ -dependent dopamine release. The pharmacological profile of this action favours a ganglionic type of nicotinic receptor, but molecular biological techniques have revealed several subtypes of nicotinic receptors in the CNS. The ...
It's very easily affected by nicotine, research shows. This is especially true for young people, because this part of the brain doesn't finish developing until about age 25. Nicotine acts like a key to unlocking special receptor(感受器)molecules on the outside of cells in the brain, ...
Nicotine acts on ni... Benowitz,N L - 《Annu Rev Pharmacol Toxicol》 被引量: 1425发表: 1996年 Evidence that Tobacco Smoking Increases the Density of ()3H]Nicotine Binding Sites in Human Brain In a postmortem study of nicotinic receptors in human brain, cigarette smoking was found to be...
through this March’s release, “Should Have Danced.” Nicotine Dolls’ fourth single, “Should Have Danced” is an impassioned fever dream full of hope, longing, and electric energy that asserts them as one of the best up-and-coming acts in New York City; it’s compelling from start to...
Nicotine acts at nicotine acetylcholine receptors (nAChRs) in the midbrain ventral tegmental area to increase locomotion and DA overflow in the nucleus accumbens and to support its self-administration (Vezina et al, 2007). Activation of nAChRs has also been implicated in the self-administration of...