KawataT,MimuroT,Onuki,etal.The K~+ATP channel opener nicorandil:effect on renal hemodynamic in spontaneously hypertensive and Wistar Kyotorats.Kidney International Supplement. 1998Kawata T, Mimuro T, Onuki T, Tsuchiya K, Nihei H, Koike T. The KATP channel opener nicorandil: effect on renal ...
nicorandilcromakalimKATP-channel activationpotentiation of adenosine-induced vasodepressionratsSummary— The effect of nicorandil on systemic blood pressure (SBP) and heart rate (HR) responses to adenosine was compared with that of cromakalim, an adenosine triphosphate (ATP)-sensitive K+ channel opener,...
Recently, much higher dose of tempol (100 mg/kg/day in drinking water, 12 days) than that in the present study has no effect on the body weight, blood glucose and blood pressure in STZ rat [52], although same higher dose of tempol has hypotensive effects in hypertensive rats ...
Recently, much higher dose of tempol (100 mg/kg/day in drinking water, 12 days) than that in the present study has no effect on the body weight, blood glucose and blood pressure in STZ rat [52], although same higher dose of tempol has hypotensive effects in hypertensive rats [50]. ...
Regionally, nicorandil decreased renal blood flows but enhanced blood flows to the brains and adrenals. It is concluded that nicorandil lacks beneficial effects on the ischaemic myocardium in pigs with a concentric coronary artery stenosis. Apparently, the potential adverse effect (decrease in coronary...
Blood pressure (BP) is a powerful cardiovascular (CV) risk factor that acts on the arterial wall and is responsible in part for various CV events, such as ... Safar,E M. - 《Circulation》 被引量: 2678发表: 2003年 Vasculopathy in Turner syndrome: arterial dilatation and intimal thickening...
nicorandil, whereas the high dose of nicorandil significantly up-regulated those expressions compared to non-treated SHRs.ConclusionsThese data indicate that nicorandil prevents hypertension-related bladder dysfunction in the SHR, which may be related to its effect on the increased blood flow in the ...
(13.1% vs. 15.5%;p= 0.02) and confirmed the cardioprotective effect of nicorandil in patients with CAD.68From this trial, no data were reported on the effect of nicorandil on angina symptoms or quality of life. At 6 months, 29.6% of patients assigned to nicorandil discontinued their study ...
An experimental study of the effect of two vasodilators, carvedilol (B blocker with alpha-antagonist) and nicorandil (NO donor) on nonalcoholic fatty liver (NAFLD) induced by hypercholesterolemia and fatty diet in rats through studying the possible anti-inflammatory and antioxidant mechanisms. Main ...
Investigates the effect of K[sub ATP] channel opener nicorandil on renal hemodynamics in hypertensive and Wistar Kyoto rats. Decrease of mean arterial blood pressure in rats; Proximal tubular stop-flow pressure of rats; Modulation of preglomerular vascular resistance by K[sub ATP].Kawata...