Acute toxicity LD50 rat (mg/kg): 1200-1300 orally, 800-1000 intravenously. Originator Chugai (Japan) Uses Nicorandil is a vasodilator used for the prophylaxis and treatment of angina. This medication widens blood vessels thus increasing the blood and oxygen flow to the heart. It is not ...
MPO, which is considered a marker of inflammation and neutrophil infiltration, uses the produced hydrogen peroxide to generate potent oxidant hypochlorite which can cause direct cytotoxicity (Abdelrahman and Abdel-Rahman 2019; Adams et al. 2010; Du et al. 2016). In APAP model, oxidative stress ...