Then, the more active species B might undergo oxidative addition with 1 to give intermediate C, during which a radical process is likely involved based on the results obtained from Fig. 6a, b. Finally, reductive elimination from C delivers the C(sp3)–C(sp) coupling product and regenerates...
Ligand-promoted cobalt-catalyzed radical hydroamination of alkenes Article Open access 07 February 2020 Nickel-catalysed enantioselective alkene dicarbofunctionalization enabled by photochemical aliphatic C–H bond activation Article Open access 29 April 2024 Nickel-catalyzed acylzincation of allenes with...
Ni-Catalyzed Remote Radical/Cross-Electrophile Coupling Cascade for Selective C(sp(3))-H Arylation An innovative 1,5-HAT cascade strategy has been advanced for the nickel-catalyzed distal arylation via cross-electrophile coupling. Through specific migrat... YT Wen,XT Kong,HC Liu,... - 《Organi...
Nickel‐catalyzed umpolung CS radical reductive cross coupling of S‐(trifluoromethyl)arylsulfonothioates with alkyl halidesChinese Chemical Letters (IF 9.4)Yu-Zhong Yang, Gui-Fen Lv, Ming Hu, Yang Li, Jin-Heng Li Pub Date: 2023-05-22 Enantioselective C(sp3)–C(sp3) Reductive Cross-Electrophi...
rather than V’.Selectiveβ-hydride elimination at theα-position of boronic ester group and following migratory insertion generates a boron group stabilized alkyl nickel intermediate VI.The intermediate VI reacts with the aryl chloride to deliver the 1,1-arylboration product 4 and regenerate the ...
2cKongandco-workers,2d,3a,j,kShuetal.,3iZhangetal.,2handourgroup.3gHowever,allthesereactionsinvolveafaciallyselectivearylmetalationoftheincorporatedolefinicunitastheenantiodeterminingstepfollowedbyterminationwithanorganohalideoranorganoboron(Scheme1A).Therefore,itishighlydesirabletoestablishnewstrategiesfor...
Nitriles are versatile and highly desired chemical intermediates for a range of products. Their economic large-scale production requires highly efficient and selective synthesis. The nickel-catalyzed hydrocyanation of C=C double bonds provides such selec
This latter radical reacts very fast with the sulfur atom, affording the C−S cross‐coupling product and a [(phen)Cu(I)] species. Then, the halogen ligand is exchanged by the aryl thiol, regenerating the catalytic active species. This proposal contrast with the OA/RE route proposed by ...
c With Lewis base adduct as the base precursor. d Detection of by-products. e Involvement of cyclometallic intermediate. f Effect of radical scavenger for the standard reaction and EPR experiment on the reaction mixture. Full size image Monitoring the C(sp2)−H borylation reaction of 1a in ...
(Fig.6a). Together, these results indicate that the reaction might proceed via the π-allylnickel intermediate, and the radical intermediates is unlikely involved. The stereochemistry of this carbonylative coupling reaction was also examined by using (R)-1afas the starting material (Fig.6b): the...