A nitrogen and phosphorus ligand-free catalytic system derived from inexpensive [(diglyme)NiBr2] allowed for efficient direct CH bond alkylations of heteroarenes with unactivated β-hydrogen-containing alkyl halides under basic reaction conditions.Lutz Ackermann...
摘要: A nitrogen and phosphorus ligand-free catalytic system derived from inexpensive [(diglyme)NiBr2] allowed for efficient direct CH bond alkylations of heteroarenes with unactivated β-hydrogen-containing alkyl halides under basic reaction conditions.关键词:...
Title reaction proceeds smoothly in the presence of a phosphor- and nitrogen-free NiBr2—CuI—diglyme catalyst system to afford C-2 alkylated benzoxazoles (III) and benzothiazoles (V) in moderate yields.doi:10.1002/chin.201221033Lutz Ackermann...
A nitrogen and phosphorus ligand-free catalytic system derived from inexpensive [(di-glyme)NiBr2] allowed for efficient direct C-H bond alkylations of heteroarenes with unactivated β-hy-drogen-containing alkyl halides under basic reaction conditions....