23. Niacin has been shown to suppress TNF-α-induced release of proinflammatory chemokines thus reducing chemokine MCP-1 (CCL2)-induced recruitment of macrophages into the atherosclerotic lesions18,24,25,26. Interestingly, recentin vitroandin vivostudies have revealed anti-inflammatory...
2,3. The NAD molecule participates in many biochemical transformations, including several reactive centers. Nearly 88% of enzymes that rely on NAD are involved in catabolic pathways. Approximately half of these enzymes are related
The function of niacin in the human body is the precursor of the nicotinamide nucleotide coenzymes NAD and NADP. NAD is essential for energy-producing reactions and NADP for anabolic reactions. Moreover, NAD also participates in unique non-redox adenosine diphosphate–ribose transfer reactions that ...