such asBRCA1/2, and mismatch repair (MMR) genes, where classification and management guidelines are better defined. Which genes to include in these panels is determined both at local and regional levels by healthcare institutions and policymakers31. Factors influencing this decision include access to...
an area-based measure of relative deprivation, derived from residents’ postcodes based on census statistics for overcrowded housing and other factors, and believed to be the main confounding factor relating to both the exposure (i.e. the decision to attend screening), and the outcome....