Using non-human primate (NHP) retinal explant culture, we aim to overcome barriers to donor human iPSC (induced pluripotent stem cell)-derived RGC survival and integration. Methods : NHP eyes were collected 5-30 minutes after euthanasia, transported in CO2 buffered Ames media, retinas islated ...
Assessment of safety and immunogenicity of MHC homozygous iPSC-derived CD34+ hematopoietic progenitors in an NHP modelKey Points Infusion of iHPs is safe and well tolerated in NHPs. iHPs are hypoimmunogenic and can be administered with a low risk of alloimmunization....