瞬时受体电位香草酸亚型1(TRPV1)内脏敏感性目的:观察电针"天枢""上巨虚"对腹泻型肠易激综合征(IBS-D)模型大鼠精神状态,内脏敏感性及结肠组织神经生长因子(NGF),酪氨酸激酶受体A(TrkA),瞬时受体电位香草酸亚型1(TRPV1)表达的影响,探讨电针干预IBS-D的可能机制.方法:将36只雄性SPF级SD大鼠随机分为空白组,模型...
The expressions of TRPV1 in the prostate, bladder and DRG in the EAP group were significantly higher than those in the control group. The expressions of NGF and TrkA in the DRG in the EAP group were significantly higher than those in the control group. The levels of serum TNF‐α and ...
Conclusions The findings of this study are instrumental for understanding the underlying causes of rosacea and could potentially lead to the development of new treatments targeting the NGF–TrkA–TRPV1 pathway. The identification of this pathway as a therapeutic target could represent a major break...
Erratum to: Electroacupuncture at st36 relieves visceral hypersensitivity via the ngf/trka/trpv1 peripheral afferent pathway in a rodent model of post-inflammation rectal hypersensitivity [erratum] (J Inflamm Res. 2021, 14, 325–339)doi:10.2147/jir.s306309Y. Chen...
Giannantoni A, Conte A, Farfariello V, Proietti S, et al. Onabotulinumtoxin-A intradetrusorial injections modulate bladder expression of NGF, TrkA, p75 and TRPV1 in patients with detrusor overactivity. Pharmacol Res. 2013;68(1):118–24....
Giannantoni A., Conte A., Farfariello V., Proietti S., Vianello A., Nardicchi V., Santoni G., Amantini C. Onabotulinumtoxin-A intradetrusorial injections modulate bladder expression of NGF, TrkA, p75 and TRPV1 in patients with detrusor overactivity. Pharmacol. Res. 2013; 68 :118–...
Nerve growth factor (NGF) seems to play a role in determining urgency and DO. Recent studies showed that NGF decreases in patients with DO who respond to ona...Amy Elliott
Giannantoni A., Conte A., Farfariello V., Proietti S., Vianello A., Nardicchi V., Santoni G., Amantini C. Onabotulinumtoxin-A intradetrusorial injections modulate bladder expression of NGF, TrkA, p75 and TRPV1 in patients with detrusor overactivity. Pharmacol. Res. 2013; 68 :118–...