ChAT and p75NGFR immunostaining of basal forebrain cholinergic neurons showed morphological changes in MAM animals, as revealed by cellular atrophy, reduced dendritic arborization and decreased staining intensity. In the cerebral cortex of microencephalic animals, reduced levels of NGF compared to ...
Antibodies against mouse NGF were also without effect on ChAT activity in cultures of dissociated septal neurons, though these cells also responded to NGF with an increase in ChAT activity. Anti-NGF blocked the effect of exogenous NGF but failed to reduce basal ChAT activity in these cultures. ...
Top Abstract This chapter introduces a practical model for teacher educators concerned with designing online courses for inservice teachers' technological knowledge learning and its implementation in their teaching. A double-layered CoP model has been developed and repeatedly applied in the teacher professi...
In this issue of Neuron, Tsui-Pierchala et al. (2002) show that in rodent SCG neurons NGF activates Ret, the signaling component of the multisubunit GDNF receptor, in vitro and in vivo by a mechanism, which is independent of GFL ligands and GFRα coreceptors. NGF-dependent Ret phosphoryla...
Regional analysis of NGF protein levels in Alzheimer's disease: Relation to chat activity : S.A. Scott, J. Weingartner, C.E. Clendening∗, K.A. Skau∗, and K.A. Crutcher. Department of Neurosurgery & College of Pharmacy∗, University of Cincinnati, Cincinnati OH 45267-0515 USAShow ...
This cell death results in a loss of selective neuronal populations and the neurotransmitters that they synthesize and release. In Alzheimer's disease, the loss of basal forebrain cholinergic neurons results in a reduction of acetylcholine and its synthesizing enzyme, choline acetyltransferase ( ChAT )...
Serotonin (5‐HT) is an evolutionarily conserved monoaminergic neurotransmitter found in the central nervous system and peripheral nervous system across in... A Biradar,CB Ganesh - 《Anatomical Record Advances in Integrative Anatomy & Evolutionary Biology》 被引量: 0发表: 2024年 Synthesis and Struct...
Recovery of ChAT immunoreactivity in axotomized rat cholinergic septal neurons despite reduced NGF receptor expression. Eur. J. Neurosci. 9 (7), 1340-1349.Naumann T, Straube A, Frotscher M (1997) Recovery of ChAT immu- noreactivity in axotomized rat cholinergic septal neurons despite re- duced...
C. (1995). Regulation of TrkA and ChAT expression in developing rat basal forebrain: Evidence that both exogenous and endogenous NGF regulate differentiation of cholinergic neurons. J. Neurosci. 15: 2888–2905.Li, Y.; Holtzman, D.M.; Kromer, L.F.; Kaplan, D.R.; Chua-Couzens, J.; ...
Levels of NGF, p75NGFR, and ChAT immunoreactivity in brain of adult and aged microencephalic rats. Neurobiol Aging 1996; 17: 137-142.Cimino M, Cattabeni F, Di Luca M, Peruzzi G, Andena ML, Tirassa P, et al. Levels of NGF, p75NGFR and ChAT immuno- reactivity in brain of adult ...