and Navia B. A. ( 2000 ) NFkappaB activation, TNF-alpha expression, and apoptosis in the AIDS-Dementia-Complex . J. Neurovirol. 6 , 537 – 543 .Rostasy K, L Monti, C Yiannoutsos, J Wu, J Bell, J Hedreen and BA Navia (2000) NFΚB activation, TNF-α expression and apoptosis...
摘要 Host organisms use different innate immune mechanisms to defend against pathogenic infections, while tight control of innate immunity is essential for proper immune induction and balance. Here, we reported that apoptotic induction orcaspase-3overexpression caused dramatic reduction of differently trigger...
Figure 9. Mitochondrial Control of Apoptosis 10楼2015-09-17 15:46 回复 huangjiexinghu 初二年级 11 五、细胞代谢相关通路:(1)胰岛素是控制关键的能量代谢功能如葡糖和脂代谢过程中的主要激素。胰岛素激活胰岛素受体酪氨酸激酶,后者磷酸化并召集不同的底物接头蛋白如IRS家族蛋白。IRS上酪氨酸被磷酸化后成为...
Apoptosis: AGT, BCL2A1 (BCL-X), BCL2L1, BIRC3 (c-IAP1). Other Factors Involved in NFκB Pathway: Kinases: AKT1, MAP3K1, RAF1. Transcription Factors: ATF1, EGR1, ELK1, FOS, JUN, STAT1. Other Genes: CARD11, CASP1 (ICE), CASP8, CFLAR (CASPER), HMOX1, MALT1, PSIP1, ...
[11] Huang J, Wang Y, Guo J, et al. Radiation-induced apoptosis along with local and systemic cytokine elaboration is associat ed with DC plus radiotherapymediated renal cell tumor re gressionDl. Clin Immunol, 2007 , 123 (3) : 298-310. ...
A pleiotropic transcription factor present in most cell types, which is involved in many biological processes such as inflammation, immunity, differentiation, cell growth, tumourigenesis and apoptosis. It forms a homo- or heterodimeric complex with Rel-like domain-containing proteins RELA/p65, RELB, ...
NF-kB Signaling Pathway Nuclear factor kB (NF-kB) is a nuclear transcription factor that regulates expression of a large number of genes that are critical for the regulation of apoptosis, viral replication, tumorigenesis, inflammation, and various autoimmune diseases. The activation of NF-kB is ...
产品介绍NFκB, a pleiotropic transcription factor, is present in almost all cell types and is involved in many biological processes including inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFκB is a homo- or heterodimeric complex formed by the Rel-like domain-cont...
apoptosis and inflammation. NFKB1 (p50) is a 50KDa functional sub-unit of NF-kB and a member of Rel protein family which is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing nuclear localization signal, DNA-binding and dimerization domains....
NFkB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFkB is activated by various intra- and extracellular stimuli such as cytokines,...