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Finally, nuclear IκB proteins do not contain the N-terminal signal-dependent phosphorylation sites, or the C-terminal PEST region, but they are still classified as IκB family, considering that they have ankyrin repeats and are capable of binding to NF-κB subunits, namely p50 homodimers only...
For English-only applications, the .en models tend to perform better, especially for the tiny.en and base.en models. It was observed that the difference becomes less significant for the small.en and medium.en models. Acknowledgements The section above was retrieved from the README of Matthias...
S1B, C). Contrary to the above data, in comparison to that treated with IL-1β only, YAP overexpression significantly reduced the expression of COL2A1 but increased the expression of MMP13, MMP3 and ADAMTS5 (Fig. 3I), as well as COX2 and iNOS (Fig. 3J), indicating that YAP ...
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Treatment of JNK inhibitor SP600125 only inhibited TNFα-induced upregulation of Adamts5 and Mmp3. However, treatment of TAK1 inhibitor 5Z-7-Oxozeaenol (5Z-7-O) greatly inhibited all TNFα or IL1β effects and evoked a broad suppression of Adamts and Mmp expression (Supplementary Figure 7b...
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