Within the field of CRC research, there have been significant developments in understanding the role of the tumor microenvironment; stromal invasion and the local immune response are well recognized as important prognostic features.23, 24 Consensus molecular subtypes and phenotypic subtypes of CRC have ...
it was mentioned that the downregulation of HSF1, SP1, and NF-κB by NZ28 can reduce the NK-activating ligands MICA/B on the cancer cells [94]. Split hand and foot malformation 1 (SHFM1) participates in the induction of the NF-κB ...
Recent developments in neurofibromatoses and RASopathies: management, diagnosis and current and future therapeutic avenues. Am J Med Genet A 2015;167A:1–10. 50. Kratz CP, Rapisuwon S, Reed H, et al. Cancer in Noonan, Costello, cardiofaciocutaneous and LEOPARD syndromes. Am J Med Genet ...
Majeed W et al (2014) Breast cancer: major risk factors and recent developments in treatment. Asian Pac J Cancer Prev 15(8):3353–3358 Article PubMed Google Scholar Khodabandeh Z et al (2022) The potential role of nicotine in breast cancer initiation, development, angiogenesis, invasion, ...
This paper reviews the recent developments in understanding the dual roles of NF-κB in cell death and survival and explores its possible usefulness in treating neurological diseases. This paper will summarize the genes regulated by NF-κB that are involved in cell death and survival to elucidate ...
Based on this, continued advancements in understanding the biology of MEs, along with developments in nanotechnology and drug delivery systems, will be key to unlocking their potential in treating MIRI. While the idea of using MEs for myocardial injury is promising, it is important to note that ...
Moreover, recent developments made to multidimensional liquid chromatography and mass spectrometry, including the FT-Orbitrap detector technology, have significantly advanced the discovery proteomics field (8). We have used this untargeted quantitative approach to identify proteins correlating with lymph node...
This may be attributed to the recent developments in antiretroviral treatment and the competence of the HIV team in the Aegean University Medical Faculty Infectious Diseases and Clinical Microbiology Department.Guliyeva, GünelAkyol, DenizPulluku, Hüsnü...
This review will focus on these newer developments by providing supporting experimental evidence and identifying key unanswered questions that may be pursued in future investigations. Genotoxic agent-induced NF-κB activation The role of ataxia telangiectasia mutated (ATM) in DNA damage response When a ...
The ORF7a protein may be a desirable target for strategic developments to minimize uncontrolled inflammation in COVID-19 patients.Similar content being viewed by others The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV Article 18 January 2021 ...