Ⅱ型神经纤维瘤病(NF2)是一种遗传性肿瘤易感综合征,导致前庭神经鞘瘤(VS)和其他中枢神经系统(CNS)肿瘤的形成。临床NF2遵循NF2 基因的遗传改变,该基因破坏了细胞膜相关蛋白merlin的功能。虽然梅林的作用尚不完全清楚,但主要认为它通过影响对接...
接触器式中间继电器NF22E-NF31E-NF40E-41-12-13-14 接触器品牌 乐清科旭机电有限公司 5年 查看详情 ￥22.00 湖北黄冈 SG307-F-V2-150 02-139490威格士压力继电器 二通式 威格士品牌 武穴黎翔机电设备有限公司 3年 查看详情 ￥1.01/个 广东深圳 G6J-2P-Y-3VDC 信号类 通信继电器 欧姆龙 批次23+ 欧...
2.MatteoIannacone, LucaG Guidotti. Immunobiology and pathogenesis of hepatitis B virus infection. Nat Rev Immunol. 2021; DOI:10.1038/s41577-021-00549-4. 3.WuT,LiJ,ShaoL,et al;Chinese group on the Study of Severe Hepat...
在高等植物中,该基因家族的成员对油脂合成和积累、植物的生长发育及抗逆等方面都有重要影响。有研究指出高等植物来源的nf-y基因在camv35s启动子驱动下或其他种子特异启动子如未改造的napin启动子会使得植株发育异常,或种子萌发异常(muetal.,2008,plantphysiology,148:1042-1054;tanetal.,2011,plantphysiol,156:1577-...
The following primary antibodies were used: NEMO (1:500 or 1:1000, GTX107582, lot #39946), GAPDH (1:25,000, GTX100118, lot #41577) from Genetex. phospho IKKα/β (Ser176/180) (1: 500, clone 16A6, cat #2697 S, lot #13), phospho p65 (Ser536) (1:500, clone 93H1, cat...
The term inflammation was used as early as 1600 BC in Egyptian papyrus writings to describe a complex series of events induced by a wound or an infection. These events can be recognized by the redness, swelling, fever and pain observed, and are now known to reflect the vasodilation, increase...
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1573-1577 View in ScopusGoogle Scholar 45 J.R. Kroep, M. Ouali, H. Gelderblom, A. Le Cesne, T.J. Dekker, M. Van Glabbeke, et al. First-line chemotherapy for malignant peripheral nerve sheath tumor (MPNST) versus other histological soft tissue sarcoma subtypes and as a prognostic ...
13, 1577–1585 (2006). 36. Lee, E. W. et al. Ubiquitination and degradation of the FADD adaptor protein regulate death receptor-mediated apoptosis and necroptosis. Nat. Commun. 3, 978 (2012). 37. Tenev, T. et al. The Ripoptosome, a signaling platform that assembles in response to ...
The third genotype–phenotype relationship evident in NF1 is that associated with largeNF1deletions and is the topic of this review. An estimated 4.7–11% of all NF1 patients have large deletions encompassing the entireNF1gene and its flanking regions at 17q11.2 (Cnossen et al.1997; Rasmussen...