NF-kappa-B p65 产品名称: NF-kappa-B p65 产品编号: RT1426 产品介绍 相关产品 产品询价 PI3-kinase p110 subunit delta Smad3 SKA3 Rac / Cdc42 SOD1 TNFR2 WEE1 MRP6 RSK1 Phospho(Thr 348) JNK2 LSM4 MDM2 IL-1β LDL Recepr Rho 新手...
对NF-κB/p65在KOA导致的慢性疼痛及关节破坏的进展速度上所发挥的作用进行研究.研究目的本研究目的是通过关节内注射MIA建立的KOA大鼠模型,探索脊髓内NF-κB/p65信号通路在KOA导致的疼痛敏感的形成过程中的作用及其机制.研究方法1,采用随机数字法将健康的雌性SD大鼠为三组:对照组,KOA模型组和NF-κ B抑制剂二硫代...
NF—kappaB抑制剂PDTC抑制IL一113诱导软骨细胞 生成NO的实验研究 华中科技大学同济医学院附属协和医院(武汉 430022) 刘建湘 杜靖远 刘日光 易诚青 提要 为探讨PUIE对IL-113诱导的大鼠软骨细胞生成N0的影响,寻找抑制N0生成的新途径。分离并培养大鼠软骨细胞,加入 ...
免疫抑制剂NF-κB水飞蓟素肿瘤坏死因子Silymarin is a polyphenolic flavonoid derived from milk thistle (Silybum marianum) that has anti-inflammatory, cytoprotective, and anticarcinogenic effects. How silymarin produces these effects is not understood, but it may involve suppression of NF-kappa B, a ...
NF- kappaB p65抗体; NF-B p65 Antibody 价格: 价格电议 产品详情: 公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不... 包装规格:50ug 用途:WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000 用途:见爱必信官网...
(p65/RelA). Both of these subunits exhibit sequence homology to the protooncogene c-Rel. The p50 has an isoform called p49/p52,and both proteins are derived from the amino-terminal of precursor protein p105 and p100. The p50/p65 heterodimer remains in the cytosol in an inactive form as a...
3)NF-kappaB inhibitorNF-kappaB抑制剂 4)nuclear factor kappa B (NF-κB)核因子kappaB(NF-κB) 5)NF-kappaB pathwayNF-kappaB信号通路 1.Reporter gene assay was performed to reveal the relationship between RAP2B gene and NF-kappaB pathway.方法应用半定量RT-PCR方法检测了27例手术切除的肺鳞癌肿瘤组织...
Silymarin blocked the translocation of p65 to the nucleus without affecting its ability to bind to the DNA. NF-kappa B-dependent reporter gene transcription was also suppressed by silymarin. Silymarin also blocked NF-kappa B activation induced by phorbol ester, LPS, okadaic acid, and ceramide, ...
RelA（p65）、c-Rel和RelB的C端存在反式激活结构域（transactivation domain，TD）使得其激活目标基因。p50和p52只有RHR而缺乏TD，因此，p50和p52同源二聚体并不能激活基因转录，而是作为一种抑制分子存在，它们在细胞内通常各自以其前体p105和p100的形式存在。NF-κB- DNA复合物 NF-κB结合DNA的结构最早是在成熟B...