critical care alerts) and supporting research computational requirements (e.g., omics data analysis). To achieve accuracy, one must address the predicted heterogeneity and poor quality of data while also adopting a paradigm shift towards
Vaccines continue to be our best tool to limit the impact of SARS-CoV-2. For example, there remain >17.5 M at-risk individuals and their contacts (>65 yrs old, care home residents, clinical risk groups and their carers/household contacts, frontline health workers, and social care wor...
intranasal administration [[92], [93], [94], [95],111,113,115,121], the possibility of formulating them in nasal dosage form, with reduced complexity for end-users (i.e., clinicians and health care organizations) with respect to parenteral formulations, could be relevant for market ...
If the present trend continues, by 2050 the number of AD patients will surpass 16 million with ~$1.1 trillion in healthcare costs thereby necessitating the development of novel therapeutic strategies to effectively treat AD. The pathological hallmarks of AD are abnormal accumulation of amyloid beta ...
(read depth of 6x), known to cause thyroid dyshormonogenesis type 6 and congenital hypothyroidism21, was also identified. However, this 24-year-old patient presents fully normal thyroid function, with repeated normal thyroxin and thyrotropin values measured over several years. The sequencing data ...
The vaginal microbiota plays a significant role in health and disease of the female reproductive tract. Next-generation sequencing techniques based upon the analysis of bacterial 16S rRNA genes permit in-depth study of vaginal microbial community structu
The vaginal microbiota plays a significant role in health and disease of the female reproductive tract. Next-generation sequencing techniques based upon the analysis of bacterial 16S rRNA genes permit in-depth study of vaginal microbial community structu
Induction of adipogenesis (mesoderm; confirmed by oil red O staining) (a), osteogenesis (mesoderm; confirmed by alizarin red S staining) (b), hepatogenesis (endoderm; confirmed by immunofluorescent detection of albumin) (c) and neurogenesis (ectoderm; confirmed by immunofluorescent detection of MAP...