In order to analyze and interpret next-generation sequencing (NGS) data, we formed a multi-skilled team composed of scientists with a background in biology, informatics, pharmacology, mathematics, medicine or engineering. The team met regularly once every 1-2 weeks to set tasks and worked ...
Next-generation sequencing (NGS)-based molecular tests have revolutionized the practice of medicine with the ability to personalize diagnosis, risk assessment, and treatment of patients with cancer and non-neoplastic disorders. Given the vast amounts of quantitative and complex sequencing data generated ...
The advent of next-generation sequencing technologies has greatly promoted advances in the study of human diseases at the genomic, transcriptomic, and epig... Riyue,Bao,Lei,... - 《Cancer Informatics》 被引量: 85发表: 2014年 Technical Considerations for Reduced Representation Bisulfite Sequencing wi...
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GeneMed: An Informatics Hub for the Coordination of Next-Generation Sequencing Studies that Support Precision Oncology Clinical Trials.GeneMed: An Informatics Hub for the Coordination of Next-Generation Sequencing Studies that Support Precision Oncology Clinical Trials.doi:10.4137/CIN.S17282GeneMed...
Next-Generation Sequencing Solutions Enable Deeper Insights into the Tumor Microenvironment Immuno-oncology (I/O) therapies are considered to be promising anti-cancer treatments and are generating hope and excitement among researchers, clinicians, and patients. The Ion Torrent portfolio...
cDNA, complementary DNA; CNV, copy number variation; FFPE, formalin-fixed paraffin-embedded; MSI, microsatellite instability; NGS, next-generation sequencing; PCR, polymerase chain reaction; SNV, single nucleotide variation; TMB, tumor mutation burden. An important disadvantage of amplicon-based enrichme...
Sensitivity required to detect cell-free DNA and cell-free RNA in research blood samples Ion Torrent next-generation sequencing systems Scalable targeted NGS to support small and large projects The Ion GeneStudio S5 system is a scalable, targeted-...
A Holzinger - 《IEEE Intell Informatics Bull》 被引量: 39发表: 2014年 Liquid biopsies in lung cancer-time to implement research technologies in routine care? next-generation sequencingpersonalized medicineLung cancer is the leading cause of cancer mortality. A substantial progress in the understanding...
An Introduction to the Informatics of "Next‐Generation" Sequencing Next-generation sequencing (NGS) packs the sequencing throughput of a 2000's-era genome center into a single affordable machine. However, software develope... LD Stein - John Wiley & Sons, Inc. 被引量: 21发表: 2011年 加载...