The application of rapidly growing CRISPR toolboxes and methods has great potential to transform biomedical research. Here, we provide a snapshot of up-to-date CRISPR toolboxes, then critically discuss the promises and hurdles associated with CRISPR-based nuclear genome editing, epigenome editing, an...
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Files v1.3.6 .github build guacd playground server web .dockerignore .gitignore .golangci.yml Dockerfile LICENSE README.md build.sh config.yml config.yml.example get_arch.sh go.mod go.sum main.go wx.png Top
Berkovitch-Yellin, A. Zaytzev-Bashan, S. Meyer, C. Paulke, F. Franceschi, A. Yonath Characterization and preliminary attempts for derivatization of crystals of large ribosomal subunits from Haloarcula marismortui diffracting to 3 Å resolution J. Mol. Biol., 222 (1991), pp. 11-15 View ...
Deltcheva, E. et al. CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. Nature 471, 602–607 (2011). CAS PubMed PubMed Central Google Scholar Gasiunas, G., Barrangou, R., Horvath, P. & Siksnys, V. Cas9-crRNA ribonucleoprotein complex mediates specific DNA...
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