Asthma: pathogenesis and novel drugs for treatment. Asthma affects almost 20 million people in the United States and more than 300 million people worldwide. Of these, 10-15% have severe asthma, which is refractory to commonly available drugs. New drugs are needed because those that are cu.....
Pharmacodynamics of antibiotics deal with the time-course of drug activity and mechanisms of action of drugs on bacteria. In particular, the bactericidal activity of β-lactams such as the cephalosporins is dependent upon the time that serum concentrations remain above the minimum inhibitory ...
Bronchodilators are central drugs in the management of patients with chronic obstructive pulmonary disease (COPD). Indacaterol was the first agent of the novel family of very long-acting β2-agonists to be used as an inhaled bronchodilator for COPD and provides 24-hour therapeutic...